基因组基础模型
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全球首个百亿级可部署基因组基础模型诞生
Ke Ji Ri Bao· 2025-10-22 23:36
Core Insights - The launch of Genos, the world's first deployable genomic universal foundational model with over 100 billion parameters, was announced by BGI Life Sciences Research Institute and Zhijiang Laboratory [1][2] - Genos supports ultra-long context analysis of up to one million base pairs and achieves precise identification at single-base resolution [1] - The model integrates high-quality human genomes from various authoritative public resources, covering 636 "telomere-to-telomere" level genomes, enhancing the understanding of human genetic diversity [1] Model Performance - Genos demonstrates a 92% accuracy rate in interpreting pathogenic mutations directly related to clinical applications, which increases to 98.3% when combined with scientific foundational models [1] - The model surpasses existing best-level models in multiple comprehensive evaluations [1] Accessibility - Genos is fully open-sourced on platforms like HuggingFace and Modao, offering two versions with 1.2 billion and 100 billion parameters to meet diverse needs [2]