Core Viewpoint - The National Immunization Program in China will include the HPV vaccine this year, marking a significant expansion after 17 years, aimed at protecting women's health [1][2]. Group 1: HPV Vaccine Inclusion - The HPV vaccine will be a bivalent type, primarily targeting school-aged girls, indicating a shift from childhood vaccination to a life-cycle approach [1]. - HPV types 16 and 18, which are responsible for 70%-80% of cervical cancer cases, will be the focus of the bivalent vaccine [1]. - Cervical cancer is the second leading cause of cancer-related deaths among women globally, with China accounting for 23% of cervical cancer cases and 16% of deaths worldwide [1][2]. Group 2: Government Initiatives - The Chinese government has been promoting free HPV vaccination for eligible girls, with 18 provinces and several cities already including it in public service projects, covering approximately 60% of eligible girls [2][3]. - The World Health Organization recommends that member countries include HPV vaccination in their national immunization programs, targeting girls aged 9 to 14 [2]. Group 3: Vaccine Supply and Awareness - The widespread promotion of HPV vaccination has increased public awareness and willingness to vaccinate, with 82% of surveyed individuals expressing a desire to vaccinate their daughters [3]. - The national immunization information system has achieved full coverage, enabling dynamic monitoring of HPV vaccination status [3]. Group 4: Production and Pricing - Since 2021, domestic production and research capabilities for HPV vaccines have significantly improved, with two bivalent vaccines approved and widely used [4]. - The price of the bivalent HPV vaccine has dropped significantly due to centralized procurement, with the lowest bid now at 27.5 yuan per dose, less than one-tenth of the initial price [4]. Group 5: Future Directions - The inclusion of the HPV vaccine in the national immunization program is expected to integrate with cervical cancer screening, forming a comprehensive prevention strategy [5]. - The National Health Commission is preparing a five-year plan to gradually align China's immunization program with international standards, including the addition of new vaccines and optimization of existing vaccination schedules [5].