Core Points - Former President Biden is reported to have been diagnosed with aggressive prostate cancer that has metastasized to the bones, raising concerns about his health during his presidency [3][5] - Ezekiel Emanuel, a former COVID-19 advisor to Biden, stated that Biden likely had cancer for several years, possibly since the beginning of his presidency [1][4] - Biden's cancer has a Gleason score of 9, indicating a high level of malignancy, and is classified as stage four, meaning it has spread [3][5] Group 1 - Biden's cancer diagnosis was made public after he reported urinary symptoms, leading to the discovery of a small nodule on his prostate [3] - The statement from Biden's office indicated that while the cancer is aggressive, it is hormone-sensitive and can be effectively managed [3] - Emanuel expressed concerns about the lack of regular health checks for sitting presidents, highlighting the importance of transparency in health matters [1][4] Group 2 - Experts have noted that once prostate cancer spreads to the bones, it is generally considered incurable, although some patients may survive for several years [5] - Former President Trump publicly expressed his support for Biden, wishing him a successful recovery, while also criticizing Biden's cognitive abilities [5][6] - Biden has faced multiple health challenges throughout his life, including two brain aneurysms in 1988 and the loss of his son to an aggressive brain cancer in 2015 [5]

2025.05. 19 本文字数：1282，阅读时长大约2分钟 作者 | 第一财经 孙卓 美国前总统拜登办公室周日（5月18日）发表声明说，拜登被诊断出患有恶性前列腺癌，而且癌细胞 已经扩散到骨骼。 诊断书显示，拜登在格里森评分（Gleason score）中被评为9分，格林森评分是评估前列腺癌症恶 性程度的病例分级系统，最严重为10分。 "虽然这是一种更具侵袭性的疾病，但是这种癌细胞似乎对激素的治疗敏感，这使得疾病能够得到有 效管理。"拜登办公室的声明说。 几天前，拜登的一位发言人表示，前总统最近因在前列腺上发现一个"小结节"而接受了检查。 声明还说，82岁的拜登和家人正在与他的医生一起探讨治疗方案。 "道格（哈里斯丈夫）和我得知拜登总统被诊断出前列腺癌，感到难过。在此期间，我们将他和 美国国立卫生研究院(NIH)称，前列腺癌是一种发生在前列腺组织中的癌症，是美国男性最常见的癌 症，也是第二大癌症死亡原因。 匹兹堡大学医学中心泌尿肿瘤学教授戴维斯（Benjamin Davies）博士表示，根据前列腺癌细胞在 显微镜下的影像，可以将其划分为不同的等级，称为格里森评分，而格里森评分为9"意味着它是最 具侵袭性的 ...

Group 1 - Prostate cancer is the second most common tumor type among men globally, with approximately 1 in 9 men diagnosed in their lifetime [1][2] - President Biden has been diagnosed with malignant prostate cancer, with cancer cells having spread to his bones, and his Gleason score is reported to be 9, indicating a highly aggressive form of the disease [1][2] - The treatment options for prostate cancer are diverse and should be personalized based on individual patient circumstances, potentially involving a combination of therapies such as hormone therapy, chemotherapy, or radiation [3] Group 2 - Recent advancements in the development of new prostate cancer drugs have been made, with the FDA approving enzalutamide (brand name: Xtandi) for a new indication in November 2023, marking it as the first approved treatment for high-risk non-metastatic castration-sensitive prostate cancer [3] - The five-year survival rate for metastatic prostate cancer in China is reported to be less than 50%, with 20%-30% of patients already having metastasis at the time of initial diagnosis [2] - Prostate cancer typically has a slower progression compared to other malignancies, allowing patients to maintain a relatively normal life and quality of life even in high-risk cases [3]

Core Points - Former President Biden has been diagnosed with malignant prostate cancer that has metastasized to the bones [1] - The Gleason score for Biden's cancer is 9, indicating a highly aggressive form of prostate cancer [2] - Despite the severity, the cancer appears to be responsive to hormone therapy, allowing for effective management of the disease [1][2] Medical Insights - Prostate cancer is the most common cancer among men in the U.S. and the second leading cause of cancer death [2] - The Gleason score is a grading system that assesses the aggressiveness of prostate cancer, with a score of 9 being classified as highly aggressive [2] - Factors such as blood prostate-specific antigen levels, imaging tests, and biopsy results are crucial for determining the cancer's behavior and optimal treatment [2] - The five-year relative survival rate for prostate cancer is approximately 98% [2] Treatment Considerations - Treatment plans for high-risk prostate cancer patients can be personalized and may include hormone therapy, chemotherapy, or radiation [2] - New hormone therapies and chemotherapy options have shown impressive efficacy in extending patient survival [2] Responses from Public Figures - Former President Trump expressed sadness over Biden's diagnosis and extended best wishes for a speedy recovery [4] - Vice President Harris also conveyed her support, highlighting Biden's resilience [4] - Former President Obama shared his concern and confidence in Biden's ability to overcome this challenge [5]