Core Insights - The Gates Foundation has announced a new commitment to donate $1.6 billion to the Global Alliance for Vaccines and Immunization (Gavi) over the next five years [1] - Since its establishment in 2000, the Gates Foundation has invested over $30.6 billion in vaccine research, production, and delivery [1] - The foundation's total donations to Gavi amount to $7.7 billion, making it the largest recipient of grants from the Gates Foundation [1]