Core Viewpoint - The timing of meals, influenced by genetic factors, significantly impacts blood sugar metabolism and diabetes risk, suggesting that adjusting meal times could be a key strategy in diabetes prevention [6][14][17]. Group 1: Genetic Influence on Eating Habits - Genetic factors control meal timing preferences, with the first meal's timing having a heritability of 59.2% and peak caloric intake timing having a heritability of 34.5% [16][19]. - Delaying meal times by one hour increases the risk of blood sugar fluctuations [7][12]. - Late eating is associated with higher BMI and waist circumference, even when controlling for sleep, age, and gender [11][12]. Group 2: Impact of Meal Timing on Metabolism - Eating later in the day is linked to poorer insulin sensitivity and higher fasting insulin levels, indicating a greater risk of insulin resistance [15][17]. - The concept of a "metabolic clock" suggests that meal timing is crucial for managing blood sugar levels and preventing type 2 diabetes [10][18]. Group 3: Recommendations for Meal Timing - Adjusting meal times, such as having the main meal three hours earlier, can significantly improve blood sugar levels and insulin sensitivity [18][19]. - Personalized dietary plans based on genetic characteristics are essential for effective management of eating habits and metabolic health [19].