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癌症早期诊断
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“科学与中国——千名院士·千场科普”2026年主场系列活动在京启动
Xin Lang Cai Jing· 2026-01-31 22:36
Group 1 - The event "Science and China - Thousands of Academicians, Thousands of Popular Science" was launched on January 30, 2026, at the Chinese Academy of Sciences, featuring engaging lectures on the theme "Following the Laws of Nature" [3][4] - Academician Jiang Lei presented on "The Mesoscopic World of Life," discussing the internal mechanisms of ultra-low energy consumption in living organisms and the exploration of quantum-limited superfluid theory [3] - Researcher Wang Shutao focused on "Capturing Cancer Cells," highlighting breakthroughs in early cancer diagnosis using antibody-modified graphene materials for ultra-sensitive capture of circulating tumor cells [3] Group 2 - The event was organized by the Academic Work Bureau of the Chinese Academy of Sciences and hosted by the Institute of Physical Science and Technology, aiming to enhance public engagement with basic science, cutting-edge technology, and public health technology [4] - The series of activities in 2026 will continue to invite more academicians and experts to engage with the public through various formats such as lectures, interactive experiences, and result displays, promoting scientific literacy among the populace [4]
新型成像系统可区分癌细胞与健康细胞
Ke Ji Ri Bao· 2025-12-29 01:13
随后,团队在培养的乳腺癌细胞、小鼠肿瘤组织及健康组织样本中对该系统进行了检验,结果显示,肿 瘤样本中SERS信号高度集中,健康组织中则仅检测到极低背景信号,体现了系统的高灵敏度与可靠的 鉴别能力。此外,通过更换靶向分子,该方法也可拓展至其他癌症类型。 该系统专为捕捉表面增强拉曼散射(SERS)纳米粒子的微弱信号而设计。这些纳米粒子可特异性结合 肿瘤标志物,系统通过读取其拉曼信号,自动标示出可能含有肿瘤组织的区域。 新系统能快速区分癌细胞与健康细胞,灵敏度显著提升,可检测到强度仅为同类商用系统1/4的拉曼信 号。尽管它暂时无法取代病理学方法,但可作为快速筛查工具,加速诊断流程,实现肿瘤更早发现、减 少诊断延误。 该系统的灵敏度提升,源于将可调波长的扫描源激光器与超灵敏探测器——超导纳米线单光子探测器 (SNSPD)相结合。SNSPD使用能检测单光子的超导纳米线,可在低背景噪声下高速捕获极微弱光信 号。SERS纳米粒子表面涂覆透明质酸,能与肿瘤细胞表面蛋白结合。初步实验显示,系统灵敏度可达 飞秒级别。 美国密歇根州立大学科学家研发出一种新型拉曼成像系统,能通过检测附着于肿瘤的纳米粒子所发出的 极微弱信号,有效区分 ...