Core Viewpoint - The article highlights the release of the "International Guidelines for Clinical Management of Diabetes in Pregnancy," which sets new standards for the management of diabetic patients during pregnancy, emphasizing a comprehensive approach from preconception to postpartum care [4][31]. Group 1: Overview of Guidelines - The guidelines are structured around "ten scenarios corresponding to ten solutions," providing evidence-based recommendations for the entire pregnancy cycle [4]. - This is the first cross-continental joint guideline released in five years, recognized for its authority by experts at the ENDO2025 conference [4]. Group 2: Key Recommendations for Preconception Diabetes Management - Preconception diabetes (PDM) refers to diabetes diagnosed before pregnancy, with a doubling of prevalence over the past 20 years, leading to increased risks during pregnancy [6]. - All women of childbearing age with diabetes should be asked about their pregnancy plans during medical visits [8][10]. - Effective screening should include promoting the necessity of preconception health management and assessing contraceptive needs [10]. Group 3: Medication Management - Type 2 diabetes patients should discontinue GLP-1 receptor agonists (GLP-1RA) before conception to avoid risks associated with sudden discontinuation [15][16]. - The routine combination of metformin with insulin therapy in pregnant women with type 2 diabetes is not recommended due to insufficient evidence [18][19]. Group 4: Dietary Recommendations - Daily carbohydrate intake should be individualized, with recommendations ranging from less than 175 grams to regular intake, balancing the need for blood sugar control and fetal development [20][22]. - Monitoring blood sugar levels is crucial, with specific targets set for fasting and postprandial glucose levels during pregnancy [26][27]. Group 5: Monitoring and Management During Pregnancy - Both continuous glucose monitoring (CGM) and traditional fingerstick monitoring are acceptable methods for blood sugar monitoring [24]. - The guidelines suggest that insulin pump therapy should be prioritized for type 1 diabetes patients, with a focus on using smart closed-loop systems [28]. Group 6: Postpartum Management - Professional diabetes management is essential postpartum, including for patients who have experienced pregnancy termination or miscarriage [30][31].