乳腺癌是中国女性健康的最常见恶性肿瘤之一。根据国家癌症中心最新统计，2022年中国乳腺癌新发病 例数为35.72万例，在女性癌症中仅次于肺癌，占癌症新发病例数的15.6%。 国际年轻乳腺癌共识专家组将40岁以下患者定义为年轻乳腺癌。复旦大学肿瘤医院在2007年至2020年登 记的66201例乳腺癌患者的数据显示，我国小于40岁乳腺癌患者占所有乳腺癌比例约14.9%，小于35岁 者占6.5%。 年轻乳腺癌患者由于发病年纪尚轻，治愈后有更多参与职场的机会和需求，承担的社会和家庭角色功能 更多更复杂，对生活质量的要求更高。 马飞表示，很多乳腺癌患者担心肿瘤会复发，也担心肿瘤会遗传给孩子，所以不敢生，还有些是客观条 件上没办法生育，乳腺癌的化疗、内分泌治疗导致的卵巢早衰和损伤都会导致患者不孕不育。内分泌治 疗至少5年，有些患者甚至需要10年、个别长达15年。如果是25岁开始接受10年治疗，结束时也已经35 岁了。 马飞表示，很多乳腺癌患者担心肿瘤会复发，也担心肿瘤会遗传给孩子，所以不敢生。 "我们有个统计数据，超过50%的年轻乳腺癌患者有生育需求，但最终真正生孩子的不到5%，这中间有 10倍大的差距，我们可以理解成' ...

Core Viewpoint - The establishment of the Tumor Patient Fertility Protection Alliance and the launch of the Early-Onset Breast Cancer Prevention and Fertility Health Project signify a shift in cancer treatment in China from merely addressing the disease to a comprehensive health management approach throughout the patient's life cycle [4][19]. Group 1: Background and Statistics - In 2022, China reported 357,200 new breast cancer cases, making it the second most common cancer among women [6][24]. - The proportion of young breast cancer patients in China is rising, with the median age of onset being approximately 15 years younger than in the United States [6][24]. - Over 50% of young patients express a desire for fertility, yet the pregnancy rate is less than 5% [6][24]. Group 2: Alliance and Initiatives - The Tumor Patient Fertility Protection Alliance aims to provide comprehensive fertility protection support for cancer patients, integrating expertise from various medical fields [2][7]. - The Early-Onset Breast Cancer Prevention and Fertility Health Project will focus on collaboration among academia, the public, and patients, promoting awareness of early diagnosis and fertility protection [2][19]. Group 3: Multidisciplinary Approach - A multidisciplinary treatment model is advocated to enhance the quality of life and survival rates for cancer patients, particularly in the context of fertility protection [11][19]. - Experts from various fields, including oncology, reproductive medicine, and psychology, are collaborating to create a supportive network for patients [11][19]. Group 4: Policy and Social Support - The "Healthy China Action - Cancer Prevention Action Implementation Plan (2023-2030)" emphasizes the need for comprehensive health management for cancer patients [6]. - Recent government measures aim to create a supportive environment for fertility and population development, highlighting the importance of societal involvement in health initiatives [6][7]. Group 5: Future Directions - The initiative aims to establish a national network for fertility protection among cancer patients, with clinical guidelines and educational programs to raise awareness [17][19]. - The project seeks to integrate cancer biology advancements into broader health management strategies, addressing both cancer treatment and fertility needs [17][19].