Core Insights - The World Health Organization and its International Agency for Research on Cancer reported that nearly 40% of cancer cases globally are preventable, highlighting the significant potential of prevention in reducing the global cancer burden [1][2] Group 1: Preventable Cancer Cases - Approximately 37.8% of all new cancer cases in 2022 (around 7.1 million cases) were associated with preventable factors [1] - The report identified 30 preventable carcinogenic factors, including smoking, alcohol consumption, high body mass index (BMI), lack of physical activity, and air pollution [1] - Smoking is the leading preventable carcinogenic factor, responsible for 15% of all new cancer cases, followed by infections (10%) and alcohol consumption (3%) [1] Group 2: Types of Preventable Cancers - Lung cancer, stomach cancer, and cervical cancer account for nearly half of all preventable cancer cases globally [1] - Lung cancer is primarily linked to smoking and air pollution, while stomach cancer is largely attributed to Helicobacter pylori infection, and cervical cancer is predominantly caused by human papillomavirus (HPV) [1] Group 3: Gender Disparities in Preventable Cancer Cases - The proportion of preventable cancer cases is significantly higher in men, with about 45% of new cancer cases in men being preventable, compared to approximately 30% in women [2] - In men, around 23% of new cancer cases are related to smoking, followed by infections (9%) and alcohol consumption (4%) [2] - In women, about 11% of new cancer cases are associated with infections, followed by smoking (6%) and high BMI (3%) [2]