报告说，新研究调查了30种可预防的致癌因素，包括吸烟、饮酒、高身体质量指数（BMI）、缺乏体育 锻炼、空气污染等，以及9种可致癌的感染。研究涵盖全球多国和36种癌症类型数据，确定吸烟是全球 首要的可预防致癌因素，导致所有新发癌症病例的15%，其次是感染（10%）和饮酒（3%）。 在全球范围内，肺癌、胃癌和宫颈癌占所有可预防癌症病例的近一半。肺癌主要与吸烟和空气污染有 关，胃癌在很大程度上归因于幽门螺旋杆菌感染，而宫颈癌绝大多数由人乳头瘤病毒(HPV)引起。 报告显示，男性可预防癌症病例的比例远高于女性，其占比在男性新发癌症病例中约为45%，在女性中 约为30%。男性所有新发癌症病例的约23%与吸烟有关，其次是感染（9%）和饮酒（4%）。女性所有 新发癌症病例的约11%与感染有关，其次是吸烟（6%）和高BMI（3%）。 （来源：工人日报） 据新华社日内瓦2月4日电（记者王露）每年2月4日是世界癌症日。世界卫生组织及其国际癌症研究署3 日发布最新全球研究报告指出，全球近40%的癌症病例可以预防。 报告估计，2022年所有新发癌症病例中约有37.8%（约710万例）与可预防的因素有关，这凸显了预防 在减轻全球癌症负 ...

中新网北京2月4日电 (记者 孙自法)施普林格·自然旗下专业学术期刊《自然-医学》最新发表一篇癌症研 究论文称，一项涵盖185个国家、36种癌症类型的分析显示，2022年全球近40%的新增癌症病例可能与 可改变的风险因素相关。 在本项研究中，IARC/WHO研究团队估计了全球及各国可能归因于30项可改变风险因素的癌症负担， 结合2022年的发病数据(来自185个国家的36种癌症类型)与约10年前的暴露流行情况，并在考虑风险因 素之间可能共存的前提下，计算了各风险因素与病例数量的关联。 他们指出，2022年全球1870万例新增癌症病例中，约有710万例(37.8%)能归因于这些可改变风险因素， 其中，吸烟(15.1%)、感染(10.2%)与饮酒(3.2%)是主要贡献因素，而肺癌、胃癌与宫颈癌合计约占这些 潜在可预防病例的近一半。 对于全球女性而言，人类乳头瘤病毒(HPV)或幽门螺杆菌等感染似乎是最大的癌症风险因素，与11.5% 的病例相关；而对于全球男性而言，最大风险因素是吸烟，与23.1%的病例相关。研究团队同时指出了 若干地域差异，例如撒哈拉以南非洲女性的癌症负担中，与可改变风险因素相关的比例最高(38.2 ...

新华社日内瓦2月4日电（记者王露）每年2月4日是世界癌症日。世界卫生组织及其国际癌症研究署3日 发布最新全球研究报告指出，全球近40%的癌症病例可以预防。 ...

对于全球女性而言，人类乳头瘤病毒或幽门螺杆菌等感染似乎是最大的癌症风险因素，与11.5%的病例 相关；而对于全球男性而言，最大风险因素是吸烟，与23.1%的病例相关。团队同时指出了若干地域差 异，例如东亚男性有57.2%的癌症病例与可改变风险因素相关，而拉丁美洲及加勒比地区男性的比例为 28.1%。 研究结果强调了癌症预防中的潜在机会，包括控烟、预防感染及各国因地制宜的预防策略。研究团队指 出，不同地区的数据质量与可获得性差异明显，特别是在癌症与风险因素数据经常有限的中低收入国 家。更完善的监测体系及更详细的数据将有助于增强未来估算的准确性，并改进政策制定。 （文章来源：科技日报） 国际癌症研究机构（IARC）与世界卫生组织（WHO）首次将全球可预防的癌症负担量化。对涵盖185 个国家、36种癌症类型的研究分析显示，2022年全球近40%的新增癌症病例，与可改变的风险因素相 关。研究结果提示，努力减少吸烟、感染及饮酒等，仍是癌症预防中的关键工作。相关结果3日发表在 《自然·医学》上。 癌症是全球范围内导致疾病与死亡的主要原因之一，其负担在不同地区存在差异，部分原因在于不同人 群接触到的可改变风险因素不同。这类 ...

撰文丨王聪 编辑丨王多鱼 排版丨水成文 2026 年 2 月 3 日，世界卫生组织国际癌症研究机构 （ IARC/WHO） 在国际顶尖医学期刊 Nature Medicine 上发表了题为 ： Global and regional cancer burden attributable to modifiable risk factors to inform prevention 的研究论文。 该研究揭示了 全球癌症负担与可改变风险因素之间的关联 ，研究指出， 全球有 37.8% 的癌症病例归因于 30 种可改变的风险因素，这意味着，全球 1870 万例新增癌症病例中，约有 710 万癌症病例本可以通过 干预措施避免发生。 这一惊人数据为我们敲响了警钟——癌症并非完全由遗传或运气决定，我们的日常生活方式与环境暴露在 癌症发生中扮演着关键角色。 这项研究由国际科学家团队完成，他们分析了 185 个国家和地区的 36 种癌症类型的数据，评估了 30 种 可改变风险因素 对癌症负担的贡献程度。这些因素包括吸烟、饮酒、高体重指数、缺乏运动、空气污染、 紫外线辐射以及多种感染因素等。 该研究采用了 GLOBOCAN 数 ...

本文转自【央视财经】； 一勺热汤、一杯烫茶、一碟腌菜，这些看似平常的饮食，可能正在悄悄损伤您的食管。中国是全球食管 癌患病人数与死亡人数最多的国家，那么食管癌究竟是一种什么疾病，有哪些习惯是主要元凶？ 复旦大学附属肿瘤医院胸部肿瘤多学科团队首席专家 陈海泉：颈部有食管，胸部有食管，腹腔里也有 食管，所以它横跨了身体的三个区域。食管癌是一个地区高发性的恶性肿瘤。中国食管癌每年的发病 率，都占全世界的50%以上。 在我国，食管癌的性别和地域差异很大。 从性别来看，男性食管癌患病率远高于女性； 高发区主要集中在太行山脉附近区域，如：河南、河北、山西等地，以及江苏苏北、广东汕头、福建闽 南等地。 专家指出，食管癌作为我国高发的消化道恶性肿瘤之一，最大的威胁在于早期往往没有典型症状。当患 者感到吞咽不适或出现梗阻感时，病情大多已进展到中晚期。因此，早发现、早诊断、早治疗至关重 要。 复旦大学附属肿瘤医院胸部肿瘤多学科团队首席专家 陈海泉：在非常早期的情况下，食管癌没有症 状。如果有症状，大部分都是进展期。我非常推荐做内窥镜筛查，做筛查能查出非常早期的情况，就不 需要做大手术。 警惕"烫"出来的癌症！ 为什么特定区域和人 ...

Group 1: Cancer-Causing Foods - Six common dietary habits are linked to cancer development, including pickled foods, moldy foods, and processed meats, which are recognized by the World Health Organization as carcinogenic factors [1] - High-sugar diets are considered a "fast track" for cancer cells, with a study indicating that high sugar intake is associated with increased risk for 45 diseases, including liver, pancreatic, breast, and prostate cancers [2] - Long-term excessive salt intake can damage the gastric mucosal barrier, promoting abnormal cell proliferation and increasing the risk of stomach cancer [6] Group 2: Recommendations for Healthier Eating - It is recommended to reduce daily added sugar intake to below 25 grams (approximately 6 teaspoons) [3] - To avoid the risk of esophageal and stomach cancers, it is advised to change the habit of eating very hot foods, suggesting the use of wide, shallow bowls to cool food more quickly [5] - Limiting salt intake to no more than 5 grams per day is suggested, along with being cautious of "hidden salt" in various condiments and snacks [9] Group 3: Specific Food Types to Avoid - Pickled foods can produce nitrites during the pickling process, which may form strong carcinogens when combined with gastric proteins, leading to higher rates of stomach and nasopharyngeal cancers in regions with high consumption [10] - Processed meats, especially smoked varieties, increase the risk of colorectal cancer due to carcinogenic substances produced during smoking that can damage DNA [11] - Moldy foods, particularly grains and nuts containing aflatoxins, are known carcinogens closely associated with liver cancer [13]

Core Viewpoint - A shocking incident occurred in a tumor hospital in Zhengzhou, Henan, where all 11 patients examined in one morning were diagnosed with late-stage esophageal cancer, highlighting the alarming prevalence of this disease in the region [1][3]. Group 1: Esophageal Cancer Diagnosis and Statistics - The late-stage diagnosis of esophageal cancer in 11 patients indicates that 7 to 8 of them may not survive beyond five years, which is a significant concern for healthcare professionals [3]. - Esophageal cancer is one of the top ten cancers globally, with its occurrence closely linked to poor dietary habits [5]. Group 2: Risk Factors and Lifestyle Habits - Research indicates that individuals who habitually consume hot and quickly eaten food have nearly four times the risk of developing esophageal squamous cell carcinoma compared to those who eat at moderate temperatures and chew their food thoroughly [6]. - Consuming excessively salty foods and pickled vegetables, which contain nitrites, also increases the risk of esophageal cancer [8]. - Rapid eating habits can lead to esophageal injuries, and insufficient chewing may cause damage to the esophageal mucosa, further elevating cancer risk [9]. Group 3: High-Risk Groups and Symptoms - The risk of esophageal cancer significantly increases after the age of 40, making this demographic particularly vulnerable [11]. - Emotional distress, such as chronic anger or anxiety, can cause chronic damage to the esophagus, thereby increasing cancer risk [12]. - Early warning signs of esophageal cancer include a sensation of a foreign body in the esophagus, difficulty swallowing, and chest pain, which may be mistaken for other conditions [13][14]. Group 4: Importance of Early Detection - Early detection of esophageal cancer can lead to better treatment outcomes, yet many patients only seek medical attention after experiencing significant swallowing difficulties, often indicating advanced stages of the disease [17].

Core Insights - There is a significant association between obesity and the incidence of various cancers, with at least 12 types of cancer directly related to obesity, including colorectal, liver, gallbladder, pancreatic, breast, uterine, ovarian, kidney, thyroid cancers, multiple myeloma, gastric cardia cancer, and esophageal adenocarcinoma [2][4]. Group 1: Cancer and Obesity - Obesity is considered a causative factor for several cancers, and the incidence of these cancers is increasing alongside rising obesity rates [4]. - The rise in obesity-related cancers is particularly notable among younger populations, highlighting the need for improved public health policies and lifestyle changes [4]. Group 2: Mechanisms Linking Obesity and Cancer - Chronic inflammation caused by obesity is linked to the occurrence and progression of cancer [5]. - Metabolic disorders resulting from obesity, such as insulin resistance and changes in sex hormone levels, may promote tumor cell growth and development [6]. - Obesity alters the tumor microenvironment, affecting interactions between tumor cells and immune cells, which can facilitate tumor growth [7]. - Obesity may suppress the quantity and activity of important immune cells, such as CD8+ T cells, thereby inhibiting anti-tumor immune surveillance [8]. - Changes in gut microbiota in obese patients are closely associated with breast tumor growth and poor prognosis, playing a crucial role in obesity-induced cancer development [8]. Group 3: GLP-1 and Cancer Risk - Recent research published in JAMA Network Open indicates that GLP-1 therapy significantly reduces the risk of 10 obesity-related cancers among 1.6 million type 2 diabetes patients who had no prior history of certain cancers [9]. - The specific cancers with reduced risk include gallbladder cancer (65% reduction), meningioma (63%), pancreatic cancer (59%), hepatocellular carcinoma (53%), ovarian cancer (48%), colorectal cancer (46%), multiple myeloma (41%), esophageal cancer (40%), endometrial cancer (26%), and kidney cancer (24%) [11]. - The study suggests that GLP-1 drugs may have potential benefits in cancer prevention for high-risk populations, warranting further research into the cancer-preventive effects of new-generation drugs [11]. Group 4: Weight Loss Data - In the PIONEER PLUS phase 3 study, oral semaglutide was shown to lead to an average weight loss of 9.2 kg (9.54%) and 7.0 kg (7.26%) for 50 mg and 25 mg doses, respectively, over 68 weeks [12]. - The latest OASIS 1 study reported an average weight loss of 18.34 kg (17.4%) in patients taking the 50 mg dose of oral semaglutide, indicating an improvement in weight loss outcomes [13].

Group 1 - Pancreatic cancer is known as a "silent killer" due to its high malignancy and often asymptomatic early stages, leading to late-stage diagnosis [8][9] - The five-year survival rate for pancreatic cancer is less than 10%, significantly lower than that of breast and lung cancers, which contributes to its reputation as the "king of cancers" [8] Group 2 - The pancreas functions as a "multi-functional factory," playing a crucial role in digestion and blood sugar regulation [4][6] - It secretes pancreatic juice containing various digestive enzymes that break down proteins, carbohydrates, and fats for easier absorption in the intestines [5] - Pancreatic islet cells secrete insulin and glucagon, which help maintain blood sugar balance [6] Group 3 - Risk factors for pancreatic cancer include uncontrollable factors such as age (over 55 years) and family history, which can increase the risk by 3-5 times [10][11] - Controllable high-risk factors include smoking, excessive alcohol consumption, obesity, chronic pancreatitis, and diabetes, with smoking increasing the risk by 2-3 times [14][27] Group 4 - Early detection through regular check-ups is recommended for high-risk groups, including those over 40 years old or with a family history of pancreatic cancer [15][16] - Lifestyle changes such as quitting smoking, limiting alcohol intake, maintaining a healthy weight, and following a balanced diet can significantly reduce the risk of pancreatic cancer [17][18][19][20] Group 5 - Common misconceptions about pancreatic cancer include the belief that a lack of family history negates the need for screening and that it is incurable once diagnosed [23][24] - Regular screenings and a healthy lifestyle are essential for prevention and early detection of pancreatic cancer [25]