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许国旺:勇闯代谢组学“无人区”
Xin Lang Cai Jing· 2026-02-24 23:26
Core Viewpoint - Xu Guowang, a researcher at the Dalian Institute of Chemical Physics, has made significant contributions to chromatography and metabolomics, becoming the first Chinese recipient of the Martin Award from the British Chromatography Society, highlighting his dedication to advancing separation science in response to national needs [1]. Group 1: Achievements in Chromatography - In the 1980s, China faced a critical issue with the reliance on imported gas chromatography columns, which limited industrial production. Xu took on the challenge of domesticating these columns while pursuing his PhD [2]. - Xu developed a gas chromatography expert system to support the design and manufacture of domestic columns, leading to a robust methodology for selecting these columns [2]. - He successfully implemented domestic columns in a major petrochemical project, significantly reducing costs and downtime associated with imported columns [3]. Group 2: Advancements in Metabolomics - In the mid-1990s, Xu recognized the potential of chromatography in clinical medicine and shifted his research focus to metabolomics, becoming a pioneer in this field in China [4]. - The concept of targeted metabolomics was developed by Xu's team, addressing the challenges of low metabolite concentrations and interference in complex biological samples [5]. - Xu's innovative approach combined non-targeted and targeted methods, leading to the development of a new paradigm in metabolomics, which was published in a leading journal in 2020 [6][7]. Group 3: Mentorship and Talent Development - Xu has played a crucial role in advancing China's separation science, fostering a new generation of researchers, and emphasizing the importance of nurturing young talent for the future of scientific research [7][8]. - He has been rigorous in mentoring students, ensuring high standards in their research and publications, and encouraging them to engage with the broader scientific community [8].