Core Viewpoint - The China Association for Science and Technology (CAST) Life Sciences Society Consortium is conducting the 2025 "Top Ten Advances in Chinese Life Sciences" selection, emphasizing principles of fairness, justice, and openness [1] Group 1: Selection Process - The selection process involves recommendations from member societies and evaluations by 88 senior experts in fields such as basic life sciences, biotechnology, and clinical medicine [1] - A review committee composed of the consortium's presidium conducts a meeting review to finalize the selected projects [1] Group 2: Selected Projects - The selected projects for 2025 exhibit strong innovation and broad coverage, including: - Discovery of molecules and mechanisms promoting health and longevity through calorie restriction [2] - New approaches for treating central nervous system diseases by promoting the regeneration of new neurons [2] - Innovative breeding strategies for plant resilience driven by epigenetic variations [2] - Breakthroughs in chromosome-level precision editing in plants and animals driven by AI [2] - Exploration of genetic mechanisms in deep-sea animal evolution and adaptation to extreme environments [2] - All selected research projects focus on cutting-edge life sciences and address significant health issues [2] Group 3: Historical Context and Impact - The annual selection of "Top Ten Advances in Chinese Life Sciences" has been conducted since 2015, aimed at promoting research and technological innovation in life sciences [3] - The initiative has been ongoing for 11 years, showcasing major scientific achievements in the field [3] - Following the announcement of results, experts from selected projects are invited to write and publish popular science books and hold outreach events to educate the public about new discoveries in life sciences [3]