Core Insights - The research led by the Kunming Institute of Zoology has successfully sequenced ancient dog genomes, revealing the migration history of ancient domestic dogs and providing direct evidence for cross-species co-evolution [2][3][8] - The study constructed a gene pool of 73 ancient dog genomes, including 17 sequenced genomes, with 14 samples from ancient Chinese dogs, marking the first acquisition of nuclear genome data from ancient Chinese dogs [2][3] - The findings indicate that a unique ancient dog lineage existed in China 5,000 years ago, which later intermingled with ancient dog genes from Siberia and the West, coinciding with human migrations [2][3][8] Gene Sequencing Technology - Gene sequencing technology, which reads the arrangement of DNA bases, has advanced significantly since the Human Genome Project began in 1988, with major improvements in efficiency and cost reduction over the years [3] - Currently, only BGI's BGI Genomics has achieved mass production of clinical-grade sequencing instruments in China, while other manufacturers collaborate with Illumina, Thermo Fisher, and BGI [3] Market Development - The gene sequencing market in China has experienced rapid growth, with BGI leading the sector, and the market size surpassing 24 billion yuan by 2022 [5] - The combination of technological breakthroughs and policy support has driven high-level compound growth in the industry [5] Future Implications - The research not only enhances understanding of ancient dog evolution but also provides new methodologies for cross-species co-evolution studies, suggesting that further advancements in gene sequencing technology will lead to more breakthroughs in life sciences [8]