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中国牵头的“高清脑图谱”集中发布十项成果
Xin Hua She· 2025-07-10 16:04
Core Insights - A team led by Chinese researchers is attempting to create a high-resolution "brain atlas" at the single-cell level, a significant advancement in neuroscience [1][3] - The research has resulted in ten series of achievements in mesoscopic brain mapping, published in a special issue of the journal "Cell" [1][4] Group 1: Research Achievements - The research has successfully transitioned from rodent models to primate models, highlighting the complexity of primate brains compared to rodents [3][4] - One article published in "Cell" details the whole-brain projection map of single neurons in the prefrontal cortex of macaques, which is crucial for higher cognitive functions [4] - Another article focuses on the striatum, a brain region potentially linked to consciousness, revealing significant structural and cellular type differences between macaques and rodents [4] Group 2: Technological Innovations - The research is supported by advanced autonomous technologies, including cell type analysis and neural connectivity mapping, which are essential for understanding cellular changes in diseases [4] - The imaging and morphological reconstruction technologies enable high-resolution imaging of the entire brain and facilitate high-throughput, rapid data analysis [4] Group 3: Collaborative Efforts - The series of achievements involved over 300 contributors from both domestic and international backgrounds, showcasing the capability for global collaborative research [5] - The complexity and data volume of primate brain mapping necessitate ongoing global scientific cooperation to achieve higher goals in understanding the mesoscopic brain atlas [5]