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破茧成蝶抗麻路——记山东省科学技术最高奖获得者张福仁
Qi Lu Wan Bao· 2025-06-27 15:50
Core Insights - The article highlights the significant contributions of Zhang Furun, a skin disease prevention expert, in transforming China from a recipient of leprosy technology to a technology-exporting nation, aiming to eliminate the harm caused by leprosy [1][7]. Group 1: Scientific Breakthroughs - Zhang Furun's team made a groundbreaking discovery in 2009 by identifying the risk gene for leprosy, which revealed a dual mechanism of "bacterial infection + immune genetic defects" [3][4]. - The team developed a risk prediction model that can accurately identify 1% of high-risk individuals using just a drop of blood, challenging the traditional World Health Organization approach of treating entire communities when one case is detected [4]. Group 2: Health System Innovations - A comprehensive prevention and treatment system was established in Shandong, consisting of 189 medical institutions, which allows for rapid response to new infections and significantly reduces the need for patients to travel long distances for treatment [6]. - The implementation of symptom monitoring and genetic screening has led to a drastic reduction in new leprosy cases and eliminated the death rate from adverse drug reactions [6]. Group 3: Global Impact and Knowledge Sharing - Since 2017, Zhang Furun's team has been involved in international projects, providing technical support in countries with high leprosy prevalence, such as India and Indonesia, and establishing precise prevention systems [7]. - The team has trained 67 participants from developing countries, enabling them to apply Chinese technology in their home countries [7].