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4-1BB靶点药物
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融资申购倍数超3000倍,维立志博首日最高涨127%
Group 1 - The core viewpoint of the articles highlights the successful IPO of Valiant Biopharma, which saw its stock price surge by 91.7% on its debut, reaching a market capitalization of HKD 12.97 billion [1] - Valiant Biopharma's IPO was highly sought after, with a subscription multiple exceeding 3000 times and total subscription amounting to HKD 330 billion, making it the hottest IPO in Hong Kong for July [1] - The company raised a total of HKD 1.29 billion through the issuance of 36.86 million H-shares at an offer price of HKD 35 per share, with net proceeds of approximately HKD 1.18 billion [1] Group 2 - Valiant Biopharma currently has one core product, LBL-024, a dual-specific antibody targeting PD-L1 and 4-1BB, along with 13 other candidate drugs, including 5 in clinical stages and 8 in preclinical stages [2] - LBL-024 is the first PD-L1 and 4-1BB dual-specific antibody to enter the registration clinical trial phase, with potential to become the first marketed drug targeting 4-1BB globally if approved [2] - Despite being established for several years, Valiant Biopharma has not yet commercialized its products, reporting revenues of only HKD 8.865 million in 2023, with projected no revenue for 2024 and Q1 2025 [2]