Financial Data and Key Metrics Changes - Net sales increased by 7% to $534 million, with a 6% growth at constant exchange rates (CER) [8][12] - Adjusted diluted EPS was $0.60, or $0.62 at CER, exceeding targets due to strong operational profitability improvements [8][12] - Adjusted operating income margin rose to 29.9% of sales, up 1.5 percentage points from the same quarter last year [15][22] Business Line Data and Key Metrics Changes - QIAstat sales grew by 41% at CER, driven by strong instrument placements and demand for syndromic testing [9][19] - QuantiFERON sales increased by 11% at CER, with solid gains in The Americas and EMEA [9][19] - Kayakuity, the digital PCR platform, experienced double-digit CER growth, although instrument placements were slightly below the previous year [10][19] - Sample Technologies sales were flat compared to 2024, but automated consumables showed single-digit growth [11][19] Market Data and Key Metrics Changes - Sales in The Americas rose by 7% CER, supported by strong growth in the U.S. and Mexico [21] - EMEA region sales grew by 8% CER, led by double-digit growth in France and Italy [21] - Asia Pacific region sales declined by 4% CER, with significant drops in China [21] Company Strategy and Development Direction - The company has upgraded its full-year 2025 sales outlook to 4% to 5% net sales growth at CER, up from a previous target of about 4% [12][36] - The company is focused on returning at least $1 billion to shareholders by 2028, with plans for a synthetic share repurchase of up to $500 million [13][39] - Continued investment in organic growth and innovation, alongside targeted M&A opportunities [13][39] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving upgraded targets despite a complex macro environment [12][36] - The impact of tariffs is expected to create a headwind of about 90 basis points on adjusted gross margin [37][83] - Management remains realistic yet ambitious regarding growth, particularly in light of the discontinuation of certain products [46][106] Other Important Information - The company has maintained a strong balance sheet, allowing for flexibility in investments and shareholder returns [18][39] - R&D investments were 8.9% in Q2 2025, aligned with annual targets [23] - The company is actively reviewing refinancing opportunities for convertible notes due in H2 2025 [26] Q&A Session Summary Question: What drives confidence in the guidance for Q3 given tougher comps? - Management noted that the guidance reflects a strong performance and emphasized the importance of core growth rates in Q4 due to product discontinuations [45][46] Question: Can you elaborate on the 41% growth in QIAstat? - Management indicated that respiratory testing drives most of the growth, with contributions from GI and meningitis panels, and highlighted strong instrument placements [52][54] Question: What is included in the "Other" product group? - Management clarified that "Other" includes various factors, with a significant impact from discontinued products, specifically NeuMoDx [57][59] Question: How is the M&A pipeline looking? - Management confirmed a solid pipeline for M&A opportunities, focusing on synergistic deals that create shareholder value [88][90] Question: What are the expectations for QIAcuity in the second half of the year? - Management expressed confidence in achieving targets despite cautious capital spending in research and academia [64][66]

Financial Data and Key Metrics Changes - QIAGEN reported net sales of $483 million, a 7% increase at constant exchange rates (CER) compared to Q1 2024 [7] - Adjusted diluted earnings per share were $0.50 at CER, exceeding the outlook of at least $0.50 [8] - Adjusted operating income margin rose to 29.8% of sales, up more than four percentage points from 24% in Q1 2024 [15] Business Line Data and Key Metrics Changes - Diagnostic Solutions sales increased by 11% at CER, driven by QIAstat Dx sales rising 37% and QuantiFERON sales up 16% [17] - PCR technologies delivered 14% CER growth, led by the adoption of the ChiAcuity digital PCR system [17] - Sample Technologies sales decreased by 1% CER, reflecting lower instrument sales amid cautious customer spending [18] - Genomics and next-generation sequencing sales were down 2% at CER, but QIAGEN Digital Insights saw high single-digit CER growth [20] Market Data and Key Metrics Changes - The Americas grew by 9% at CER, with strong performance in the U.S., Canada, and Latin America [20] - EMEA region delivered 8% growth at CER, with top-performing countries including Germany and Italy [21] - Asia Pacific experienced a modest decline, primarily due to weak trends in China, which represents about 3% to 4% of total sales [21] Company Strategy and Development Direction - QIAGEN reaffirmed its full-year 2025 outlook, expecting around 4% sales growth at CER and about 5% growth in its core portfolio [11] - The company is expanding options to increase returns to shareholders, proposing an annual cash dividend and a synthetic share repurchase of up to $500 million [12] - Upcoming product launches in Sample Technologies are expected to drive growth, including new automation instruments [25] Management's Comments on Operating Environment and Future Outlook - Management highlighted the resilience of the business despite a complex macro environment marked by cautious customer spending [6] - The company remains conservative in its revenue growth outlook for the second half of the year due to ongoing volatility [52] - Management expressed confidence in the strategy and execution, aiming for solid profitable growth and stronger shareholder returns [39] Other Important Information - QIAGEN is preparing for a leadership transition in its Supervisory Board, with two members stepping down after the upcoming Annual General Meeting [13] - The company is focused on maintaining strategic flexibility in a volatile environment while investing in targeted areas like R&D [11] Q&A Session Summary Question: What drove the acceleration in QuantiFERON in the quarter? - Management attributed the acceleration to a confirmation of their strategy based on constant innovations and strong global performance [44] Question: Why is there an assumption of deceleration in top-line growth for the second half? - Management described this as a realistic ambition due to ongoing volatility in the economic environment, preferring to remain prudent [52] Question: What is the current status of tariff exposure? - Management indicated that they have been well-prepared for tariff impacts and have ramped up inventory levels to mitigate effects [55] Question: What is the outlook for QIAstat after a strong first quarter? - Management confirmed guidance for QIAstat, expecting double-digit growth by the end of the year [98] Question: What is the growth expectation for Sample Technologies? - Management expects growth around 3% per year, focusing on high-value applications like liquid biopsy [81]