This story was originally published on BioPharma Dive. To receive daily news and insights, subscribe to our free daily BioPharma Dive newsletter. Dive Brief: Aktis Oncology has become the first biotechnology company to file for an initial public offering in several weeks, outlining on Friday a stock issuance to help advance a pipeline of radiopharmaceuticals for cancer. Aktis specializes in what it calls “miniprotein radioconjugates,” which it believes to be capable of accessing tumor targets that are ...

Core Viewpoint - LB Pharmaceuticals has successfully completed a significant IPO, raising $285 million, marking a notable event in the 2025 biotech IPO landscape, which had seen a drought since February [1][5]. Group 1: IPO Details - The company offered 19 million shares at a public offering price of $15 each, which is an increase from the initially planned 16.7 million shares [1][2]. - The total amount raised could increase by an additional $42.7 million if underwriters exercise an option for 2.85 million more shares at the same price [2]. - LB Pharmaceuticals began trading on the Nasdaq Global Market under the ticker LBRX on September 11, with the offering expected to close on September 12 [2]. Group 2: Use of Funds - The funds from the IPO will primarily support the development of LB-102, an oral treatment for schizophrenia, which is a derivative of amisulpride [3]. - The company plans to allocate $133 million of the IPO proceeds for a phase III study of LB-102 in schizophrenia and $25 million for a phase II trial in bipolar disorder [4]. Group 3: Market Context - The successful IPO of LB Pharmaceuticals indicates a revival in the biotech IPO market, which had not seen significant raises since February 2025 [5]. - The year began with optimism following a recovery in 2024, with several companies conducting IPOs, including Metsera and Maze Therapeutics [6]. - However, market volatility due to macroeconomic policy shifts has created an unpredictable IPO environment, leading some companies to delay or cancel their IPO plans [7][8].