As filed with the Securities and Exchange Commission on December 3, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Aspire Biopharma Holdings, Inc. (Exact name of registrant as specified in its charter) (State or jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) Delaware 2834 33-3467744 (I.R.S. Employer Identification No.) 23150 Fashion Dri ...

Table of Contents As filed with the Securities and Exchange Commission on October 24, 2025 Registration No. 333-__________ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 WINDTREE THERAPEUTICS, INC. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) Delaware 2836 94-3171943 (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identif ...

Core Points - Aptera Motors Corp. has entered into a share purchase agreement for up to $75 million of committed equity financing with New Circle Principal Investments LLC [1][2] - The financing allows Aptera to issue and sell up to $75 million of its Class B common stock at its discretion, subject to customary conditions [2] - Proceeds from the financing are intended to support production readiness for Aptera's Launch Edition vehicles, providing flexibility to raise capital in stages [3] Company Overview - Aptera Motors Corp. is a solar mobility company focused on developing highly efficient solar electric vehicles, leveraging advancements in aerodynamics, material science, and solar technology [5] - The company operates as a public benefit corporation, aiming to build a sustainable business that positively impacts stakeholders and the environment [5] Investor Overview - New Circle Capital is an institutional investor that focuses on small and mid-cap public companies, investing across various industries and transaction situations [6]

Core Points - ProPhase Labs Inc. will participate in a live Virtual Non-Deal Roadshow on September 4, 2025, to discuss its latest investor presentation [2][3] - The presentation will cover a general overview of the company, its crypto treasury strategy, significant liquidity events, and the cancellation of the Equity Line of Credit (ELOC) [3] Company Overview - ProPhase Labs Inc. is a next-generation biotech, genomics, and consumer products company focused on healthcare innovation [5] - The company aims to revolutionize healthcare through Whole Genome Sequencing solutions and diagnostic developments, including a test for early detection of esophageal cancer [5] - ProPhase Labs is committed to executional excellence, smart diversification, and a synergistic omni-channel approach to health and wellness solutions [5]

As filed with the Securities and Exchange Commission on August 27, 2025 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Reliance Global Group, Inc. (Exact name of registrant as specified in its charter) (State or Other Jurisdiction of (Primary Standard Industrial (I.R.S. Employer Incorporation or Organization) Classification Code Number) Identification Number) Mr. Ezra Beyman Florida 6411 46-3390293 ...

Core Insights - OSR Holdings, Inc. provided a transparency update regarding its Equity Line of Credit (ELOC) agreement with White Lion GBM Innovation Fund, emphasizing that future issuances are not purely dilutive and will support business development [1][3]. Financing and Share Issuance - The company has issued a total of 2,308,382 shares under structured financing, with less than 10% of registered shares utilized under the ELOC agreement [7]. - The registered share capacity under the ELOC agreement is 9,500,000, with 767,500 shares issued since June 17, 2025 [7]. Business Development and Partnerships - Proceeds from financing are being invested in drug R&D, medical device initiatives, and digital asset ecosystems, with a focus on protecting shareholder value [3]. - The Woori IO clinical trial in Korea is being conducted in partnership with a major technology company in mobile and wearable devices, with further details expected after the Stock Purchase Agreement is signed [4]. Company Overview - OSR Holdings, Inc. is dedicated to advancing biomedical innovation in health and wellness, focusing on immuno-oncology, regenerative biologics, and medical device distribution [5]. - The company aims to improve patient care through cutting-edge research and development [5]. Strategic Initiatives - The company is pursuing a "Plug-and-Play" bacterial vector platform for cancer immunotherapy and a Disease-Modifying Osteoarthritis Drug (DMOAD) candidate [8]. - A strategic move is underway to acquire noninvasive glucose monitoring technology through a signed term sheet with Woori IO [8].

Core Viewpoint - Scienture Holdings, Inc. has successfully completed a draw on its Equity Line of Credit (ELOC) to support the commercial launch of its FDA-approved product, Arbli, while temporarily suspending further draws until certain conditions are met [1][2][3]. Financial Strategy - The draw on the ELOC is aimed at providing immediate capital for pre-launch activities of Arbli, the first FDA-approved ready-to-use oral liquid losartan in the U.S. market [2]. - The company has decided to pause further ELOC draws for 30 trading days or until its stock price reaches $10 per share, indicating confidence in its business prospects [3]. Product Information - Arbli is a novel antihypertensive medication indicated for treating hypertension in patients over 6 years old, reducing stroke risk in patients with hypertension and left ventricular hypertrophy, and treating diabetic nephropathy in certain type 2 diabetes patients [4]. - The product is available in a 165 mL peppermint-flavored suspension that does not require refrigeration and has an 18-month shelf life when stored at room temperature [5]. Company Overview - Scienture Holdings, Inc. operates through its subsidiaries, focusing on providing enhanced value to patients and healthcare systems by developing and distributing specialty pharmaceutical products [6]. - The company is committed to addressing unmet market needs and has a team of experienced professionals dedicated to bringing unique specialty products to market [6].