As filed with the Securities and Exchange Commission on January 30, 2023. Registration No. 333-269200 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 AMENDMENT NO. 1 TO FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Structure Therapeutics Inc. (Exact name of registrant as specified in its charter) TABLE OF CONTENTS Cayman Islands 2834 98-1480821 (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) 61 ...

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on January 12, 2023. Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Structure Therapeutics Inc. (Exact name of registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) Cayman Islands 2834 98-1480821 (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identifica ...