Core Insights - Aethlon Medical reported its fiscal Q3 2026 financial results, highlighting advancements in clinical and research programs, operational efficiencies, and ongoing technology development [1] Financial Performance - As of December 31, 2025, Aethlon had a cash balance of approximately $7.0 million [1] - Consolidated operating expenses for Q3 2026 were approximately $2.06 million, an increase of $250,000 or 13.6% from $1.81 million in Q3 2025, primarily due to higher payroll costs [1] - For the nine months ended December 31, 2025, consolidated operating expenses were approximately $5.36 million, a decrease of approximately $1.98 million or 26.9% compared to $7.34 million in the same period in 2024 [1] Operational Efficiency - The company maintained disciplined cost controls, resulting in a 26.9% decline in operating expenses year-to-date compared to the prior year [1] - Aethlon is actively progressing in its Australian oncology trial, with Cohort 2 enrollment and treatment underway, building on favorable results from Cohort 1 [1] Technology Development - Aethlon is evaluating the Hemopurifier® compatibility with a simplified blood treatment system under a Material Transfer Agreement, which may enhance its use in oncology units [1] - The company continues to advance its preclinical extracellular vesicle (EV) research platform, with recent findings on Long COVID published and submitted for peer review [1] Scientific Advancement - The R&D team is exploring the potential of the Hemopurifier to remove various EVs implicated in diseases beyond cancer, including Lupus and Cardiovascular Diseases [1] - Aethlon's research indicates that the Hemopurifier may serve as a "pipeline within a single device" for multiple therapeutic applications [1] Clinical Progress - The ongoing Australian oncology trial aims to evaluate the safety and feasibility of Hemopurifier treatments in patients with solid tumors [1] - The trial is designed to assess appropriate dosing in participants receiving anti-PD-1 agents [1] Nasdaq Compliance - Aethlon has maintained compliance with Nasdaq listing requirements, resolving all prior compliance matters [1]

Core Insights - SIGA Technologies reported financial results for the three and nine months ended September 30, 2025, highlighting a focus on securing new procurement contracts with the U.S. Government and international governments to support future revenue growth [2][3]. Financial Performance - For the first nine months of 2025, SIGA generated $86 million in product revenues and $33 million in pre-tax operating income [2]. - Product sales for the three months ended September 30, 2025, were $0.9 million, a decrease from $8.9 million in the same period of 2024. For the nine months, product sales increased to $85.8 million from $53.5 million year-over-year [3]. - Total revenues for the three months ended September 30, 2025, were $2.6 million, down from $10.0 million in 2024, while total revenues for the nine months increased to $90.8 million from $57.3 million [3]. - The company reported an operating loss of $10.2 million for the three months ended September 30, 2025, compared to an income of $0.5 million in 2024. For the nine months, operating income was $33.2 million, up from $12.9 million [3]. - Net loss for the three months ended September 30, 2025, was $6.4 million, compared to a net income of $1.3 million in 2024. For the nine months, net income was $28.7 million, up from $13.5 million [3]. Business and Operational Highlights - The company generated $53 million in oral TPOXX revenues and $26 million in IV TPOXX revenues related to deliveries to the U.S. Strategic National Stockpile [7]. - In June 2025, SIGA's BARDA 19C contract was modified to add $13 million for the TPOXX pediatric development program, totaling $27 million in development funding added during the second quarter [7]. - A procurement order for $26 million of IV TPOXX was received from the U.S. Government in March 2025 [7]. - TPOXX received regulatory approval in Japan for treating smallpox and other related conditions, marking it as the first antiviral therapy approved for orthopoxviruses in Japan [7]. Capital Management - A special cash dividend of $0.60 per share was declared on April 8, 2025, and paid on May 15, 2025 [5].

Core Insights - SIGA Technologies, Inc. is hosting a business update webcast and conference call on November 6, 2025, at 4:30 P.M. ET [1] - The call will feature CEO Diem Nguyen and CFO Daniel Luckshire [1] Company Overview - SIGA is a commercial-stage pharmaceutical company focused on developing innovative medicines for infectious diseases, particularly orthopoxviruses [4] - The company aims to protect against severe infectious diseases through partnerships with governments and public health agencies [4] - SIGA's flagship product, TPOXX® (tecovirimat), is approved in the U.S. and Canada for smallpox treatment and authorized in Europe, the UK, and Japan for smallpox, mpox, cowpox, and vaccinia complications [4]

Core Viewpoint - Impact Biomedical Inc. has received a new patent for a composition and method aimed at controlling infectious diseases, showcasing its commitment to innovative healthcare solutions [1][2][3]. Company Summary - The newly issued U.S. patent No. 12,357,584 B2 is titled "Composition and Method of Controlling Infectious Diseases with Functional Fragrances" and is part of the company's 3F™ technology platform [1][2]. - This patent expands the company's existing patent estate, which includes insect repellent and antimicrobial applications, indicating a strategic focus on addressing unmet healthcare needs [3]. - The CEO of Impact Biomedical emphasized the success of their business model in delivering proprietary technology aimed at improving human healthcare [8]. Product and Technology Summary - The patented compositions consist of plant-derived constituents and fragrances, which have demonstrated unique antimicrobial and antiviral properties [2][4]. - Potential applications of these compositions include their use as disinfectants and treatments for various infectious diseases, targeting pathogens such as E. coli, MRSA, influenza, rhinovirus, and M. tuberculosis [5][6]. - The global infectious disease market is projected to grow significantly, from $21.7 billion in 2024 to $34 billion in 2033, reflecting a compound annual growth rate (CAGR) of 5.77% [7].

Company Overview - SIGA Technologies, Inc. is a commercial-stage pharmaceutical company focused on developing innovative medicines to treat and prevent infectious diseases, particularly orthopoxviruses [4] - The company aims to protect against severe infectious diseases through partnerships with governments and public health agencies [4] - SIGA's flagship product, TPOXX (tecovirimat), is an antiviral medicine approved in the U.S. and Canada for smallpox treatment and authorized in Europe, the UK, and Japan for smallpox, mpox, cowpox, and vaccinia complications [4] Upcoming Events - Management will host a webcast and conference call on August 5, 2025, at 4:30 P.M. ET to provide a business update [1] - The call will feature CEO Diem Nguyen and CFO Daniel Luckshire [1] - A live webcast will be available on the company's website, and participants are encouraged to log in 5-10 minutes prior to the start time [2] Access and Replay Information - Participants can access the call by dialing specific numbers for domestic and international callers [2] - A replay of the call will be available for two weeks using designated numbers and Conference ID [3] - The archived webcast will also be accessible in the Investor Relations section of the company's website [3]