Parkinson's disease

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Engineering Hope: Restoring Movement in Parkinson’s Disease | Amey Desai | TEDxDJSCE
TEDx Talks· 2025-09-12 16:38
My name is ASA. I'm an engineer and uh I'm fascinated by everything. Right.Since my engineering days, I've been fascinated by everything engineering. Um motors, circuits, sensors. But the one machine that fascinates me most of all is the one we all live within the human body.And um the body is really amazing. You walk without thinking about it. your heart beats without you needing to do anything.Um everything is automatic. The body knows really, you know, but as amazing as the system is, um sometimes things ...
Karolinska Development’s portfolio company Umecrine Cognition publishes data showing sustained effect of golexanolone in a Parkinson’s disease model
Globenewswire· 2025-09-04 06:50
Core Viewpoint - Umecrine Cognition's drug candidate golexanolone shows promise in reversing neuroinflammation in a Parkinson's disease model, indicating its potential as a chronic treatment option [1][3]. Company Overview - Karolinska Development AB holds a 73% ownership stake in Umecrine Cognition prior to dilution, emphasizing its significant investment in innovative medical solutions [4]. - The company focuses on identifying and developing breakthrough medical innovations in the Nordic region, aiming to create and grow companies that advance these innovations into commercial products [5][6]. Research Findings - A preclinical study demonstrated that golexanolone completely reverses the activation of immune cells responsible for neuroinflammation in the brain, which is crucial for controlling voluntary movement and posture [3]. - The treatment with golexanolone not only reversed the increase of inflammation-promoting proteins but also provided robust protection against neuroinflammation as early as three weeks after disease onset [3]. - After nine weeks, golexanolone continued to counteract inflammation and aided in restoring protective immune cells, indicating a sustained effect on harmful brain inflammation [3]. Academic Collaboration - The study was conducted in collaboration with academic partners at Centro de Investigación Príncipe Felipe in Valencia, Spain, highlighting the importance of academic partnerships in advancing medical research [4].
THE HIDDEN DANGERS OF LIVING NEAR A GOLF COURSE...
The Diary Of A CEO· 2025-08-06 21:38
There's a study that came out. This study showed that people that lived near within a mile or so of golf courses had a much higher incidence of Parkinson's disease. Right.It says 126% higher risk. Right. Okay.So then why is that. Right. And this is where I want to get into the the pesticides issue because it's one of the ways that you induce Parkinson's disease in animals.You give them essentially a pesticide. So rotinone being one, parakquat and what that does is the mitochondrial toxin. It's important to ...
My shaky future and what a raccoon taught me about resilience | Cathy Molohan | TEDxKLU Hamburg
TEDx Talks· 2025-07-10 15:36
Parkinson's Disease Overview - Parkinson's disease affects 1 in 15 men in the Western world [4] - Parkinson's disease is growing 20% faster than Alzheimer's disease, making it the most common and fastest-growing neurological condition [5] - The biggest breakthrough in Parkinson's medication occurred over 60 years ago in 1961 [6] - Levodopa remains the standard treatment for Parkinson's disease [8] Treatment and Management - Deep brain stimulation (DBS), involving electrodes in the skull connected to a battery pack in the chest, is a treatment option [11] - DBS can significantly reduce tremors associated with Parkinson's [16] Resilience and Coping Strategies - Resilience is key to dealing with life's challenges [19] - Key traits of resilient people include having choices, being optimistic, and having goals [22] - Resilience is built over time through experience [24][25] - Creating healthy habits, both physical and mental, can foster resilience [28][29]