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BioLineRx Reports Second Quarter 2025 Financial Results and Provides Corporate Update
Prnewswire· 2025-08-14 11:00
Core Insights - BioLineRx Ltd. is making progress in evaluating assets for potential pipeline expansion in oncology and rare diseases, with a targeted transaction for 2025 [1][2] - The company has a strong balance sheet with $28.2 million in cash as of June 30, 2025, extending its cash runway into the first half of 2027 [3] - The CEO expressed confidence in executing a transaction this year to expand the pipeline and create long-term value [2] Financial Updates - Total revenues for Q2 2025 were $0.3 million, primarily from royalties related to APHEXDA, compared to $5.4 million in Q2 2024 [14][21] - Research and development expenses for Q2 2025 were $2.3 million, slightly up from $2.2 million in Q2 2024 [14][21] - The net loss for Q2 2025 was $3.9 million, a significant decline from a net income of $0.5 million in Q2 2024 [14][21] Clinical Updates - The ongoing CheMo4METPANC Phase 2b clinical trial is evaluating motixafortide in combination with cemiplimab and standard chemotherapy, with promising interim results [9] - In the treatment of metastatic pancreatic cancer, two patients showed significant responses, including one with complete resolution of liver lesions [4][5] - A Phase 1 clinical trial for motixafortide in sickle cell disease is progressing, with results expected in the second half of 2025 [10] Product Performance - APHEXDA generated sales of $1.7 million in Q2 2025, contributing $0.3 million in royalty revenue to BioLineRx [11] - The company has retained rights to develop motixafortide for metastatic pancreatic cancer, with a Phase 2b trial ongoing in collaboration with Columbia University [15][16]
Medicus Pharma's 'Savvy' Antev Deal De-Risks Pipeline Expansion, Enhances Near-Commercial Portfolio
Benzinga· 2025-05-12 18:20
Core Viewpoint - Medicus Pharma Ltd. is acquiring Antev, a clinical-stage biotech company, to enhance its portfolio with Teverelix, a potential first-in-class therapy for cardiovascular high-risk prostate cancer patients and those experiencing acute urinary retention [1][3]. Group 1: Acquisition Details - Medicus will acquire all of Antev's issued shares in exchange for 2.67 million shares, representing approximately 19% of Medicus [2]. - Antev shareholders may receive up to $65 million in contingent consideration based on future FDA approvals [2]. - The transaction is expected to close before the end of June [2]. Group 2: Market Potential and Strategic Fit - Teverelix targets an estimated $2 billion addressable U.S. market for acute urinary retention, with no approved drugs currently available for recurrence [3]. - The acquisition aligns with Medicus' strategy, as it does not overlap with existing programs and could add significant value if Teverelix progresses smoothly into Phase 3 trials [4]. Group 3: Clinical Study Updates - Medicus announced a positive interim analysis for the SKNJCT-003 Phase 2 clinical study for treating basal cell carcinoma, showing over 60% complete clinical clearance among subjects [5]. - The investigational product D-MNA was well tolerated across both low and high-dose groups, with no dose-limiting toxicities or serious adverse events reported [5]. - The company plans to submit the interim analysis to the FDA as part of a package for a Type C meeting in Q2 2025 [6]. Group 4: Stock Performance - Following the news, MDCX stock increased by 15.8%, reaching $5.31 [6].