Company Overview - BioCryst Pharmaceuticals, Inc. is a global biotechnology company focused on developing and commercializing medicines for hereditary angioedema (HAE) and other rare diseases [3] - The company has commercialized ORLADEYO® (berotralstat), the first oral, once-daily plasma kallikrein inhibitor, and is advancing a pipeline of potential first-in-class or best-in-class oral small-molecule and injectable protein therapeutics for a range of rare diseases [3] Stock Compensation - The compensation committee of BioCryst's board of directors granted three newly-hired employees restricted stock units (RSUs) covering an aggregate of 30,700 shares of BioCryst common stock as inducements for employment [1] - The RSUs were granted as of November 3, 2025, and will vest in four equal annual installments beginning on the one-year anniversary of the grant date, subject to the new employee's continued service with the company [2] - The RSUs are subject to the terms and conditions of BioCryst's Inducement Equity Incentive Plan and a restricted stock unit agreement covering the grant [2]

Corporate Updates - Quantum BioPharma Ltd. is focused on developing innovative biopharmaceutical solutions for neurodegenerative and metabolic disorders, as well as alcohol misuse disorders [1][5] - The company has drug candidates at various stages of development, with a lead compound, Lucid-MS, aimed at preventing and reversing myelin degradation associated with multiple sclerosis [5] Debt Settlement - On August 12, 2025, the company settled outstanding debt of $26,812.50 USD with a creditor by converting it into 1,102 Class B Shares at a price of $24.33 USD per share [2] Grant of Restricted Stock Units - On August 15, 2025, the company granted 800 restricted stock units (RSUs) each to two Clinical Advisors, Peter Stys and Jack Antel, with specific vesting conditions tied to regulatory filings [3][8] - The RSUs and Creditor Shares are subject to a statutory hold period of four months and one day [3] Advisory Board Changes - The company terminated the Board Advisor Agreement with Kevin Malone effective August 15, 2025, resulting in his departure from the advisory role [4] Strategic Investments - Quantum BioPharma retains a 20.10% ownership stake in Unbuzzd Wellness Inc., which is involved in the OTC version of its product unbuzzd™, and is entitled to a 7% royalty on sales until total payments reach $250 million, after which the royalty will decrease to 3% [5] - The company also maintains a portfolio of strategic investments through its subsidiary, FSD Strategic Investments Inc., which includes loans secured by residential or commercial property [5]