Market Sentiment - The CNN Money Fear and Greed index showed almost no change in overall market sentiment, remaining in the "Neutral" zone with a reading of 44.6, slightly down from 44.8 [5][6] Stock Performance - U.S. stocks settled mostly higher, with the Dow Jones index gaining around 319 points to close at 48,382.39. The S&P 500 increased by 0.19% to 6,858.47, while the Nasdaq Composite saw a slight decline of 0.03% to 23,235.63 [4] - Key chip stocks, including Nvidia and Micron Technology, experienced gains during the session [1] Annual Gains - In 2025, the S&P 500 surged by 16.39%, marking its third consecutive year of double-digit growth. The Nasdaq Composite gained 20.36%, while the Dow added 12.97% [2] Company-Specific News - Outlook Therapeutics, Inc. saw its shares drop over 58% after the FDA issued a complete response letter regarding its biologics license application for ONS-5010/LYTENAVA, indicating that the application cannot be approved in its current form [3]