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云顶新耀:EVM14注射液临床试验申请获国家药监局受理
Zhong Zheng Wang· 2025-07-15 11:52
Group 1 - The core point of the news is that Yunding Xinyao's EVM14 injection, a universal therapeutic vaccine for tumors, has received formal acceptance for clinical trial application from the National Medical Products Administration (NMPA) in China, marking a significant step in the company's global innovation strategy [1] - EVM14 is based on Yunding Xinyao's proprietary mRNA technology platform and targets five tumor-related antigens, intended for the treatment of squamous non-small cell lung cancer and head and neck squamous cell carcinoma [1] - The company has prepared thoroughly for the clinical trials of EVM14, with the first batch of GMP clinical trial samples released from its Jiaxing factory on June 9, 2025, to support trials in both the US and China [1] Group 2 - In the mRNA treatment field, the company has proactively developed multiple mRNA therapeutic drugs, aiming to create a fully integrated and clinically validated AI+mRNA platform [2] - The company has established a comprehensive end-to-end industrial chain platform that enhances efficiency from antigen design, mRNA sequence optimization, LNP delivery technology to large-scale production [2] - During the "mRNA Innovation Technology Platform R&D Day" held at the end of June, the company revealed that it has engaged with multiple top 20 global pharmaceutical companies, attracting interest for collaboration from several multinational pharmaceutical firms [2]