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CMS (867.HK; 8A8.SG) Signed A Distribution Agreement for Ophthalmic Drugs Lucentis® and Beovu®
Globenewswire· 2025-10-27 14:24
SHENZHEN, CHINA, Oct. 27, 2025 (GLOBE NEWSWIRE) -- China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that on 27 October 2025, the Group through its subsidiary CMS VISION INTERNATIONAL MANAGEMENT LIMITED entered into a Distribution Agreement (the “Agreement”) with Novartis Pharma Services AG (“Novartis”) for Ranibizumab Injection (“Lucentis®”) and Brolucizumab Injection (“Beovu®”). In accordance with the Agreement, the Group has obtained the exclusive right to import, distri ...
JNJ vs. MRK: Which Blue-Chip Pharma Stock Should Be in Your Portfolio?
ZACKS· 2025-10-27 14:21
Key Takeaways J&J's pharma and MedTech strength drive growth despite Stelara LOE and ongoing legal challenges.MRK relies heavily on Keytruda, while new drugs like Capvaxive and Winrevair support diversification.J&J's solid cash flows, 63-year dividend record and 2026 growth outlook make it a stronger portfolio choice.Johnson & Johnson (JNJ) and Merck (MRK) are leading U.S. healthcare giants, making them natural peers for a head-to-head comparison.Both companies have a strong presence in oncology, immunology ...
Seeking Clues to Lilly (LLY) Q3 Earnings? A Peek Into Wall Street Projections for Key Metrics
ZACKS· 2025-10-27 14:17
Wall Street analysts expect Eli Lilly (LLY) to post quarterly earnings of $6.02 per share in its upcoming report, which indicates a year-over-year increase of 410.2%. Revenues are expected to be $16.01 billion, up 40% from the year-ago quarter.Over the past 30 days, the consensus EPS estimate for the quarter has been adjusted upward by 0.3% to its current level. This demonstrates the covering analysts' collective reassessment of their initial projections during this period.Prior to a company's earnings anno ...
Ahead of Bristol Myers (BMY) Q3 Earnings: Get Ready With Wall Street Estimates for Key Metrics
ZACKS· 2025-10-27 14:16
Analysts on Wall Street project that Bristol Myers Squibb (BMY) will announce quarterly earnings of $1.51 per share in its forthcoming report, representing a decline of 16.1% year over year. Revenues are projected to reach $11.83 billion, declining 0.5% from the same quarter last year.Over the past 30 days, the consensus EPS estimate for the quarter has been adjusted downward by 0.6% to its current level. This demonstrates the covering analysts' collective reassessment of their initial projections during th ...
Global Markets Surge as Geopolitical Tensions Simmer; Argentina Peso Jumps Post-Election
Stock Market News· 2025-10-27 13:39
Key TakeawaysU.S. equity markets opened strongly on Monday, October 27, 2025, with the Dow Jones Industrial Average (DJIA), Nasdaq (NDAQ), and S&P 500 (SPX) all posting significant gains, led by a 1.46% surge in the Nasdaq.Geopolitical tensions remain a key focus, as China's Commerce Ministry firmly opposed UK actions against Chinese firms, while WTO Director-General Okonjo-Iweala acknowledged the validity of U.S. criticisms of the global trading system.Argentina's peso (ARS=) jumped 10% following Milei's m ...
LLY Stock To $1,100?
Forbes· 2025-10-27 13:25
Core Insights - Eli Lilly (LLY) shares have increased by 16% over the past month, currently priced at $825, reflecting a positive trend in U.S. pharmaceutical stocks due to drug pricing agreements with the Trump Administration [1][3] - The company has committed over $50 billion towards domestic manufacturing expansion, raising speculation about potential similar agreements to enhance its market position [3] - A multifactor analysis suggests that now may be an opportune time to purchase additional shares of LLY, with a target price of $1074 deemed achievable [4] Financial Performance - Eli Lilly's revenue has grown by 37% over the last 12 months, increasing from $39 billion to $53 billion, with quarterly revenues rising by 37.6% to $16 billion [10] - The company has demonstrated strong profitability, with an operating income of $23 billion and an operating margin of 43% [10] - Eli Lilly's net income for the last 12 months was approximately $14 billion, resulting in a net margin of about 25.9% [10] Market Position and Valuation - Eli Lilly has a market capitalization of $741 billion, with a debt amounting to $40 billion, leading to a debt-to-equity ratio of 5.4% [10] - The stock has shown resilience during economic downturns, recovering fully from declines that were less severe than those of the S&P 500 [8][10] - Despite a very high valuation, the stock is considered attractive but volatile, indicating potential for both gains and risks [4][5]
Clearmind Medicine Appoints Mary-Elizabeth Gifford as Chief of Global Impact to Advance US Partnerships and Governmental Engagement
Globenewswire· 2025-10-27 13:22
Core Insights - Clearmind Medicine Inc. has appointed Mary-Elizabeth Gifford as Chief of Global Impact to enhance US partnerships and regulatory advocacy in the psychedelic medicine sector [1][3] Company Overview - Clearmind is a clinical-stage biotech company focused on developing novel neuroplastogens-derived therapeutics to address under-treated health issues, including alcohol use disorder [4] - The company holds an intellectual property portfolio consisting of 19 patent families with 31 granted patents and aims to expand this portfolio opportunistically [5] Leadership and Expertise - Mary-Elizabeth Gifford previously served as Chief of Global Impact at Psyence BioMed and has extensive experience in psychedelic policies and regulatory landscapes [2][3] - Gifford has been recognized as a significant figure in the psychedelic industry, being named a "Psychedelic Titan" and described as "the most quietly influential woman working in psychedelics today" [3] Strategic Initiatives - Gifford's role will focus on bridging research, regulation, and patient care to accelerate the advancement of innovative psychedelic medicines [1][3] - Clearmind is conducting clinical trials at prestigious institutions such as Yale School of Medicine and Johns Hopkins University, aiming to set industry standards for scientific rigor [3]
Bristol-Myers Squibb: Earnings Champion Valued Like A Loser (NYSE:BMY)
Seeking Alpha· 2025-10-27 13:13
Bristol-Myers Squibb Company (NYSE: BMY ) share price performance has been weak since "Liberation Day," which mirrors the performance of the entire healthcare industry due to significant political uncertainty. As a result, it might seem that myI am a highly experienced Chief Financial Officer (CFO) with a strong background in the oilfield and real estate industries. With over a decade of experience in finance, I have led numerous complex due diligence efforts and M&A transactions, both domestically and inte ...
Bristol-Myers Squibb: Earnings Champion Valued Like A Loser
Seeking Alpha· 2025-10-27 13:13
Bristol-Myers Squibb Company (NYSE: BMY ) share price performance has been weak since "Liberation Day," which mirrors the performance of the entire healthcare industry due to significant political uncertainty. As a result, it might seem that myI am a highly experienced Chief Financial Officer (CFO) with a strong background in the oilfield and real estate industries. With over a decade of experience in finance, I have led numerous complex due diligence efforts and M&A transactions, both domestically and inte ...
Neumora Therapeutics (NasdaqGS:NMRA) 2025 R&D Day Transcript
2025-10-27 13:02
Summary of Neumora Therapeutics 2025 R&D Day Conference Call Company Overview - **Company**: Neumora Therapeutics (NasdaqGS: NMRA) - **Event**: 2025 R&D Day held on October 27, 2025 - **Key Participants**: Paul Burns (CEO), Josh Pinto (President), Nick Brandon (Chief Scientific Officer), Bill Arora (Chief Operating and Development Officer), Dr. Anton P. Porstenson (Alzheimer's expert) Core Industry and Company Insights Alzheimer's Disease and NMRA-511 - **NMRA-511**: A vasopressin 1a receptor antagonist aimed at treating agitation in Alzheimer's disease, which affects over 70% of individuals with Alzheimer's dementia [39][40] - **Unmet Need**: Current treatments have limited efficacy and significant side effects, creating a demand for safer, more effective options [45][62] - **Clinical Evidence**: Preclinical studies indicate that B1A receptor antagonists can reduce agitation symptoms, supported by various studies showing the involvement of the vasopressin system in emotional regulation [40][41] Obesity Treatment and NMRA-215 - **NMRA-215**: A next-generation NLRP3 inhibitor designed for obesity treatment, showing promising weight loss results in preclinical studies [7][13] - **Weight Loss Data**: NMRA-215 demonstrated up to 19% body weight loss as a monotherapy, comparable to leading injectable GLP-1s [14][27] - **Combination Therapy**: When combined with semaglutide, NMRA-215 achieved 26% weight loss, indicating potential for enhanced efficacy in obesity treatment [30][31] Key Data and Findings NMRA-215 Clinical Data - **DIO Models**: NMRA-215 showed dose-dependent weight loss, with significant reductions in food intake and preservation of lean mass compared to semaglutide [15][33] - **Biomarker Improvements**: NMRA-215 also demonstrated positive effects on cardiovascular biomarkers, suggesting additional health benefits beyond weight loss [36] NMRA-511 Clinical Data - **Phase I Study**: NMRA-511 has shown a favorable safety profile in healthy adults and elderly participants, with no serious adverse events reported [42][43] - **Phase Ib Study Design**: The ongoing study aims to assess the efficacy of NMRA-511 in reducing agitation symptoms in Alzheimer's patients, with multiple outcome measures to evaluate its impact [44][72] Strategic Vision and Future Outlook - **Pipeline Potential**: Neumora believes it has assembled an industry-leading pipeline with the potential to deliver significant therapeutic breakthroughs in brain diseases [10] - **Cash Runway**: The company has a cash runway extending into 2027, allowing for continued development and clinical trials across its portfolio [8] - **Upcoming Milestones**: Key data readouts for NMRA-511 and NMRA-215 are expected in the near term, with plans to initiate clinical studies for NMRA-215 in 2026 [9][37] Conclusion - Neumora Therapeutics is positioned to address significant unmet needs in the treatment of Alzheimer's disease and obesity through innovative therapies like NMRA-511 and NMRA-215. The company is focused on advancing its clinical programs while maintaining a strong financial position to support ongoing research and development efforts.