Core Insights - Hims & Hers Health, Inc. (HIMS) reported a GAAP EPS of $0.06 for Q3 2025, which was $0.04 below estimates [1] - The company's revenue for Q3 2025 reached $598.98 million, exceeding expectations by $19.13 million, representing a 49% increase compared to the same period last year [1] - For Q4 2025, the company has provided guidance, although specific figures were not disclosed in the provided text [1]

Core Insights - Larimar Therapeutics reported positive long-term data from its open label study of nomlabofusp, indicating potential to alter the disease course of Friedreich's ataxia (FA) [2][3][4] - The company plans to submit a Biologics License Application (BLA) seeking accelerated approval in the second quarter of 2026 [2][4][10] Clinical Development - In the open label study, 100% of participants achieved skin frataxin (FXN) levels over 50% of median levels in healthy volunteers after 6 months [3][4] - A median improvement of 2.25 in the modified Friedreich Ataxia Rating Scale (mFARS) score was observed after 1 year, compared to a worsening of 1.00 in the FACOMS reference population [3][4] - The company is implementing a modified starting dose regimen to mitigate the risk of anaphylactic reactions, which will also be incorporated into the Phase 3 protocol [4][10] Financial Performance - As of September 30, 2025, the company had cash, cash equivalents, and marketable securities totaling $175.4 million, with a projected cash runway into the fourth quarter of 2026 [5][10] - The net loss for the third quarter of 2025 was $47.7 million, or $0.61 per share, compared to a net loss of $15.5 million, or $0.24 per share, for the same period in 2024 [6][19] - Research and development expenses for the third quarter of 2025 were $44.9 million, significantly higher than $13.9 million for the same period in 2024, primarily due to increased manufacturing costs for nomlabofusp [7][11] Future Plans - Larimar plans to provide an update on the nomlabofusp development program, including regulatory discussions and the open label study status, in the first quarter of 2026 [10][11] - The company is focused on advancing its global Phase 3 study and preparing for patient enrollment [10][11]

Core Viewpoint - Skye Bioscience, Inc. is set to discuss its Q3 2025 financial results and business updates in a conference call on November 10, 2025, following the release of its financial results after market close [1][2] Company Overview - Skye Bioscience is a clinical-stage biotechnology company focused on developing new therapeutic pathways for obesity and metabolic health disorders through next-generation molecules that modulate G-protein coupled receptors [3] - The company is conducting a Phase 2 clinical trial for nimacimab, an antibody that inhibits CB1, and is also assessing its combination with a GLP-1R agonist (Wegovy®) [3] Upcoming Events - A live webcast of the conference call will be available on the Skye Investor Relations website, along with the earnings press release and financial tables [2] - Skye will present at the Stifel 2025 Healthcare Conference in New York on November 13, 2025, and will be available for one-on-one meetings [2]

Core Insights - The article discusses the importance of enabling Javascript and cookies in browsers to ensure proper functionality and access to content [1] Group 1 - The article emphasizes that users may face access issues if ad-blockers are enabled, suggesting the need to disable them for a better experience [1]

Core Viewpoint - Viking Therapeutics' shares surged by 44.9% in October, driven by positive developments surrounding its lead drug candidate VK2735 for obesity and type 2 diabetes [1] Group 1: Stock Movement and Market Activity - The initial rise in stock price was linked to takeover activity in the biotech sector, particularly Pfizer's attempt to acquire Metsera, which prompted speculation about potential acquisitions, including Viking Therapeutics [2][3] - The second leg of the stock increase was fueled by the initiation of a phase 1 trial for VK2735 (oral) as a maintenance dose, which reassured investors about the drug's value despite previous safety concerns [4][5] - The third leg was supported by the company's Q3 earnings report, confirming resources for phase 3 trials of VK2735 (subcutaneous) and ahead-of-schedule enrollment [6] Group 2: Future Prospects - Enrollment for the VK2735 (subcutaneous) phase 3 trials is projected to conclude by late 2025 to early 2026, with results expected by mid-2027, while phase 1 trial results for VK2735 (oral) are anticipated in mid-2026 [8]

Accessibility StatementSkip Navigation Logo: https://mma.prnewswire.com/media/1708529/Onassis_Holdings_Corp_Logo.jpg SOURCE Onassis Holdings Corp 21% NEW YORK, Nov. 5, 2025 /PRNewswire/ -- Onassis Holding Corp (OTC: ONSS) a US public company pioneering cellular rejuvenation and longevity biotechnology, is pleased to announce the appointment of Esq. Paz Itzhaki-Weinberger to its Advisory Board. Paz will lead the company's strategy on international law, trade, and cross border corporate affairs. Paz Itzhaki ...

Core Insights - TME Pharma has signed a non-binding Letter of Intent (LOI) with a German resource development company (GRDC) to explore collaboration and investment opportunities, marking a step in its investment diversification strategy aimed at building sustainable value and strengthening its financial position [2][10][12] Investment Strategy - Following a strategic review, TME Pharma intends to expand operations by integrating biotechnology expertise with profitable, cash-flow-generating investments to enhance long-term shareholder value and financial resilience while maintaining focus on its lead therapeutic assets, NOX-A12 and E36 [3][20] - The company plans to broaden the scope of its investments to include new business lines managed at the parent company level, seeking shareholder approval at the next Extraordinary General Meeting [4][20] GRDC Overview - GRDC specializes in sustainable resource development and environmental rehabilitation, utilizing advanced technologies and circular economy principles to transform underutilized mining sites into productive operations [5] - The company is finalizing a financing round to acquire machinery for resource extraction, with operations expected to start in early 2026, targeting the recovery of manganese, copper, and gold [6] Collaboration Objectives - TME Pharma aims to diversify its investment strategy into innovative and ESG-oriented industries through the potential partnership with GRDC, which could generate revenue in the short to medium term [8][10] - The transaction structure will be negotiated to minimize cash outflows and risk exposure while capitalizing on GRDC's value-creation potential [9][11] Due Diligence and Future Steps - TME Pharma will initiate due diligence procedures to assess GRDC's projections and underlying asset values, with the proposed investment to be submitted to shareholders for approval upon successful completion [7][10]

Walsh Asset Management President and CIO Kevin Mann has some rare stats that might just change your mind on at least whether at least whether to sell, right, Kevin. >> Absolutely. I mean, people are right to question how much longer this bull market can run.And we did just recently hit the three-year birthday of this current bull market in October. So, I asked my research team to go back, find out if this is a good signal or a bad signal. And what they found was that over the last 50 years, the five time th ...

Core Insights - Several healthcare and biotech companies experienced significant after-hours stock price increases following the release of strong third-quarter earnings and updated guidance for 2025 [1] Company Summaries - **Veracyte Inc. (VCYT)**: - Stock surged 16.07% to $41.92 - Reported third-quarter net income of $19.1 million, a 26% increase year-over-year - Net earnings per share rose to $0.24, up $0.05, while non-GAAP EPS reached $0.51, an increase of $0.18 - Revenue totaled $131.9 million, reflecting 14% growth from $115.9 million in Q3 2024 [2][3] - **Rigel Pharmaceuticals, Inc. (RIGL)**: - Stock jumped 23.33% to $35.00 - Posted third-quarter net income of $27.9 million, more than doubling from $12.4 million last year - Earnings per share came in at $1.46 versus $0.70 last year - Total revenue for the quarter reached $69.5 million [4][5] - **NeuroPace, Inc. (NPCE)**: - Stock rose 16.28% to $10.93 - Reported a narrower net loss of $3.5 million compared to a $5.5 million loss in the same period last year - Revenue grew 30% year-over-year to $27.4 million, up from $21.1 million [6] - **CareDx, Inc. (CDNA)**: - Stock gained 8.47% to $15.75 - Reported GAAP net income of $1.7 million, compared to a $10.6 million loss in the prior-year period - GAAP earnings per share reached $0.03, reversing a $0.20 loss per share last year - Revenue increased 21% to $100.1 million [7][8] - **FibroBiologics, Inc. (FBLG)**: - Stock edged up 5.29% to $0.3443 - Experienced a modest after-hours gain despite a steep decline of over 17% during the regular session - No new financial disclosures were issued alongside the price movement [9]

Core Insights - Ark Invest, led by Cathie Wood, made significant trades on Tuesday, notably purchasing shares in Bullish, a cryptocurrency exchange backed by Peter Thiel [1][2]. Trade Details - Ark Invest purchased a total of 23,963 shares of Bullish through three of its funds: Ark Fintech Innovation ETF, ARK Innovation ETF, and ARK Next Generation Internet ETF, with the trade valued at approximately $1.09 million based on a closing price of $45.75 [2]. - In August, Bullish increased the size and price of its upcoming initial public offering, offering 30 million shares priced between $32 and $33 each, targeting a valuation of nearly $5 billion [3]. - On the previous day, Ark Invest had purchased $11.9 million worth of Bullish stock, while Coinbase Global Inc. remains one of Ark's largest holdings, comprising 5.96% of its flagship ARKK ETF, valued at $489.9 million [3]. Other Key Trades - Ark Invest sold 20,485 shares of SoFi Technologies Inc, reducing its holdings in the ARKF ETF [6]. - The firm bought 21,865 shares of CRISPR Therapeutics AG for the ARKG ETF and 140,462 shares for ARKK [6]. - Ark Invest sold 16,952 shares of Ionis Pharmaceuticals Inc from the ARKG ETF and purchased 50,163 shares of Beam Therapeutics Inc for the ARKG ETF and 240,838 shares for ARKK [6]. - Additionally, Ark sold 25,846 shares of Adaptive Biotechnologies Corp from the ARKG ETF [6].