Core Viewpoint - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI with bio-manufacturing, green chemicals, new materials, future food, and agriculture [4][5]. Group 1: Conference Overview - The conference will explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [4][5]. - Various activities will be held concurrently, including a Youth Forum on Bio-Manufacturing, a high-level roundtable discussion, and a closed-door seminar on the "2025 AI Empowering Bio-Manufacturing Industry Innovation Development Blue Book" [4][5]. Group 2: Agenda Highlights - Day 1 will feature registration, a high-level roundtable discussion, and a Youth Forum focused on discovering innovations in bio-manufacturing [7][10]. - Day 2 will include an opening ceremony, a macro forum on the bio-manufacturing industry, and specialized forums on green chemicals and new materials, as well as a welcome dinner [8][9]. - Day 3 will focus on AI applications in bio-manufacturing, future food, and agriculture, along with technology showcases and networking opportunities [8][28]. Group 3: Supporting Organizations - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. and supported by various institutions, including Peking University Ningbo Institute of Ocean Medicine and the Zhejiang Synthetic Biology Industry Technology Alliance [5][6]. - Notable experts and organizations are involved, including Zhang Xian'en from Shenzhen University and multiple biotechnology companies [5][6]. Group 4: Industry Insights - The conference will release the "China Synthetic Biology Industry Distribution Map (2025 Edition)" and a list of over 500 representative enterprises in the bio-manufacturing sector [65][66]. - The event aims to facilitate the transfer and transformation of scientific achievements, product scaling, and talent acquisition in the bio-manufacturing industry [4][5].

Core Viewpoint - The Fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22, 2025, in Ningbo, Zhejiang, focusing on AI-enabled bio-manufacturing, green chemicals and new materials, future food, and future agriculture [9][10]. Group 1: Conference Overview - The conference aims to explore the development trends of the bio-manufacturing industry during the "14th Five-Year Plan" period, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [9][10]. - Various activities will be held concurrently, including a youth forum, high-level discussions, and a closed-door seminar on the "2025 AI Empowering Bio-Manufacturing Industry Innovation Development Blue Book" [9][10]. Group 2: Event Schedule - The event will feature a series of forums and discussions over three days, including topics on green chemicals, AI in bio-manufacturing, and future food and agriculture [14][15]. - Notable sessions include a high-level discussion with industry leaders and a youth forum aimed at discovering innovative achievements in bio-manufacturing [15][30]. Group 3: Participating Organizations - The conference is organized by Ningbo Detai Zhongyan Information Technology Co., Ltd., in collaboration with various academic and industry partners, including Peking University Ningbo Institute of Ocean Medicine and Ningbo Enzyme Science Biotechnology Co., Ltd. [10][11]. - Support is provided by several associations and alliances focused on synthetic biology and bio-manufacturing [10][11]. Group 4: Key Topics and Innovations - The conference will showcase advancements in synthetic biology, including the production of functional sugars, microbial protein synthesis, and the design of humanized collagen [37][38][40]. - Innovations in enzyme engineering and the application of AI in bio-manufacturing processes will also be highlighted [30][31].

Core Viewpoint - The article discusses the development of humanized "4D" collagen protein based on natural collagen, aiming to address the immunogenicity and pathogenic risks associated with traditional animal-derived collagen [1]. Group 1: Research and Development - The research team led by Professor Li Shuang from South China University of Technology focuses on biomimetic "honeycomb" porous structures for molecular construction, optimizing collagen triple helix sequences through gene editing [1]. - The team combines computer simulation design with cross-scale self-assembly templates to achieve a synergistic optimization of high specific surface area, strong mechanical strength, and biological activity [1]. - Techniques such as transmission electron microscopy are utilized to analyze the hierarchical structure, and in vitro cell experiments validate the biocompatibility and regenerative efficacy of the developed materials [1]. Group 2: Industry Applications - The innovative collagen material is expected to provide new biological materials for regenerative medicine, promoting upgrades in industries such as medical aesthetics and bone repair [1]. - Professor Li Shuang will present a talk titled "Molecular Design of Humanized '4D' Collagen Protein" at the SynBioCon 2025 conference, which focuses on synthetic biology and green biological manufacturing [1][14]. Group 3: Conference Details - The SynBioCon 2025 conference will be held from August 20-22 in Ningbo, Zhejiang, focusing on the intersection of AI and biological manufacturing, as well as advancements in green chemistry, new materials, future food, and agriculture [14]. - The conference will feature various activities, including a youth forum on biological manufacturing, high-level discussions on the industry, and a closed-door seminar on the "2025 Artificial Intelligence Empowering Biological Manufacturing Industry Innovation Development Blue Book" [14][15].