双特异性抗体和T细胞衔接器

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报告下载 | BI调查:关税背景下的中国生物技术授权交易活动
彭博Bloomberg· 2025-05-07 08:06
Core Insights - The article discusses the increasing trend of licensing transactions between Chinese biotechnology companies and global pharmaceutical firms amid tense US-China trade relations, with expected growth in transaction volume and upfront payments [2][6]. Group 1: Licensing Activity Trends - A survey indicates that licensing transactions between Chinese enterprises and global pharmaceutical/biotech companies are on the rise, with a median expected transaction volume growth of 5% and a median upfront payment growth of 2.5% in 2024 [6]. - In 2024, it is projected that 43 transactions will be completed, with an average upfront payment of $92.5 million and an average total value of $1.4 billion [6]. Group 2: Preferred Drug Development Platforms - Antibody-drug conjugates (ADCs) remain the most favored drug development technology platform among global pharmaceutical and biotech companies, with 36% of respondents selecting it as their top choice [12]. - Gene therapy ranks second in attractiveness at 16%, followed by bispecific antibodies and T-cell engagers at 15% [12]. - Cell therapies, including CAR-T and CAR-NK, have the lowest appeal at 1%, potentially influenced by the uneven distribution of Chinese enterprises across various treatment fields [12].