Core Viewpoint - Company is a major global supplier of tazobactam and has successfully completed the qualification process for downstream customers, which will enhance production capacity and market competitiveness [1] Group 1: Product Supply and Market Position - Company is the largest global supplier of sulbactam and the only domestic supplier certified by international standards, with sulbactam products currently experiencing a price increase [1] - Company is expanding the production capacity of piperacillin, which can be combined with tazobactam and sulbactam to form compound preparations, indicating a broad market demand [1] Group 2: Production Cost and Innovation - Company is one of the few domestic manufacturers with a full industry chain layout for carbapenem products, and the market price for carbapenem products is at a historical low, with limited room for further price declines [1] - Company is collaborating with a research team to develop a continuous flow enzyme method, which is expected to reduce the cost of carbapenem products by 15%-20% [1]

Production Capacity and Expansion Plans - The company currently has a production capacity of 8,000 tons/year for VC products and 4,000 tons/year for FEC products, with plans to increase VC capacity to 10,000 tons/year by Q2 2026 through technical upgrades [2][3] - Future capacity increases for VC and FEC products will depend on market demand and industry capacity releases, with potential targets of 20,000 tons/year for VC and 5,000 tons/year for FEC [2] Impact of Raw Material Price Changes - The price of 6-APA, a key raw material for the company's main pharmaceutical products, has decreased by 38% as of November 3, 2025, which is expected to enhance the gross margin of the pharmaceutical manufacturing business [3] - The company's pharmaceutical products, including Hezobactam and Shubactam, account for approximately 40% of total revenue in 2024 [3] Growth Opportunities in Pharmaceutical Business - The company is a major global supplier of Hezobactam and has successfully completed supplier qualification for its new production process, which is expected to reduce production costs and improve market competitiveness [4] - As the largest supplier of Shubactam, the company is experiencing a price increase trend for this product [4] - The company is expanding the production capacity of Piperacillin, which is a mainstream product with broad market demand [4] Synthetic Biology and Microbial Protein Initiatives - The company has become a pioneer in the domestic microbial protein industry, achieving a production capacity of 1,000 tons/year for filamentous fungal protein and is accelerating the construction of a project with an annual capacity of 200,000 tons for microbial protein and resource utilization [6] - The company has developed a new production strain with independent intellectual property rights and has applied for patents in nine countries, achieving international advanced levels in key production technologies [6][7] - The company’s microbial protein has received multiple international certifications, including HALAL and KOSHER, and is set to expand its market presence upon receiving new food ingredient registration [7][8] Environmental and Economic Benefits - The production process for the new protein not only efficiently converts raw materials but also produces high-value products like amino acid water-soluble fertilizers, contributing to cost reduction and economic benefits [8] - The company aims for zero emissions in its production processes, aligning with green manufacturing goals [8]

Core Viewpoint - Haisheng Pharmaceutical (002099) reported a significant decline in net profit and revenue for the first half of 2025, indicating challenges in its business performance and financial health [1]. Financial Performance - The total revenue for the first half of 2025 was 925 million yuan, a decrease of 10.94% compared to the same period in 2024 [1]. - The net profit attributable to shareholders was 14.09 million yuan, down 63.01% year-on-year [1]. - In Q2 2025, total revenue was 439 million yuan, reflecting a 14.04% decline year-on-year, while net profit was 4.86 million yuan, down 11.71% [1]. - The gross margin was 26.13%, a decrease of 7.11% year-on-year, and the net margin was 1.36%, down 61.4% [1]. - Total expenses (selling, administrative, and financial) amounted to 131 million yuan, accounting for 14.17% of revenue, an increase of 6.08% year-on-year [1]. - Earnings per share were 0.01 yuan, a decrease of 50% compared to the previous year [1]. Cash Flow and Debt - The company reported cash and cash equivalents of 1.79 billion yuan, an increase of 20.28% year-on-year [1]. - Accounts receivable decreased to 420 million yuan, down 11.06% year-on-year [1]. - Interest-bearing debt rose to 1.591 billion yuan, an increase of 29.34% [1]. - The cash flow situation is concerning, with operating cash flow per share dropping to 0.0 yuan, a decrease of 99.14% [1]. Business Evaluation - The company's historical return on invested capital (ROIC) has been weak, with a median of 5.02% over the past decade and a particularly poor ROIC of -6.54% in 2023 [3]. - The business model appears fragile, with three years of losses out of 18 annual reports since its listing [3]. Product and Market Outlook - The price of penem products has been declining but showed signs of stabilization in Q2 2025, with a generally optimistic market outlook [4]. - The company is collaborating with various original drug manufacturers in the penem sector, which may provide incremental growth [4]. - Demand for clindamycin products remains stable, with sales growth in Q1 2025 and maintained gross margins [4]. - The company is diversifying its product pipeline in areas such as anti-infection, diabetes, dermatology, ophthalmology, and psychiatry, with several products in different stages of development [4].

Group 1: Raw Material Development - The price of penicillin products has been declining but showed signs of recovery in Q2 2025, with an optimistic market outlook for sustained price recovery [1] - The global demand for clindamycin series remains stable, with Q1 sales showing a year-on-year increase and maintaining a good gross margin [1] - The company has diversified its raw material drug portfolio across various fields, including anti-infection, diabetes, dermatology, ophthalmology, and psychiatric medications, with products at different R&D stages [1] Group 2: CMO/CDMO Business Expansion - The company has seen good growth in existing collaborations with strategic clients, leading to a year-on-year increase in cooperation orders [2] - New projects are in the validation phase, with successful completion of validation for anti-infection products and ongoing global market registration changes [2] - The peptide platform is expanding its supply volume while actively seeking high-value new project collaborations to enhance revenue [2] Group 3: Formulation Business Strategy - Three formulation products have passed consistency evaluations, and one product has won a national procurement bid, with plans to expand market sales through collaborations rather than building a sales team [2] - The company aims to enrich its formulation product line and create an integrated industrial platform covering intermediates, raw materials, and formulations [2] - Ongoing collaborations with overseas formulation companies are being explored for opportunities in modified new drug development [2] Group 4: Innovation Drug Sector - The company currently does not engage in innovative drug R&D but provides CMO/CDMO services for clinical-stage innovative drugs and patented products for leading global and domestic pharmaceutical companies [2] - Investments in industry funds include projects related to HPV infection, liver cancer therapeutic vaccines, TCR-T cell therapy, and recombinant drugs [2] Group 5: Dye Market Dynamics - The company leads in the niche market of anthraquinone active blue dye products and has adjusted prices based on market conditions this year [2] - Continuous monitoring of market sales and price trends will guide timely adjustments to production plans, maintaining competitive advantages in the dye market [2]