Group 1: Core Insights - CRISPR gene editing technology is being increasingly applied in the genetic improvement of animals such as horses, sheep, and pigs, enhancing traits for safer and higher-quality meat products [1][2] - The use of CRISPR in horses has faced resistance from traditional sports organizations, highlighting the tension between technological advancement and traditional practices [2] - Companies like Acceligen are utilizing CRISPR to develop livestock that can better withstand climate change, such as the PRLR-SLICK cows, which have been recognized as safe for consumption by the FDA [3] Group 2: Industry Applications - The development of CRISPR-edited animals is showing potential in agriculture, with applications aimed at improving meat and dairy production efficiency [3][4] - The GalSafe pig, developed by Revivicor, aims to reduce allergic reactions in humans and has potential applications in organ transplantation [4] - The emergence of CRISPR-edited animals is also driven by the need for disease resistance, as seen in the genetically modified pigs that can resist specific viral infections [3] Group 3: Ethical and Safety Considerations - The rise of gene-edited animals raises ethical concerns, particularly regarding the potential health impacts on both the animals and consumers [5][6] - There are worries about unintended consequences, such as off-target mutations that could lead to health issues or early mortality in edited animals [6] - Continuous monitoring of the health impacts of gene editing on animals is deemed necessary to ensure their welfare and long-term health [6]