Core Viewpoint - The launch of the colorectal cancer gene screening project in Guangzhou represents a significant innovation in cancer prevention and control, emphasizing early screening and diagnosis through advanced technology and community engagement [1][2][3]. Group 1: Project Overview - The colorectal cancer gene screening project is jointly organized by the Guangzhou Health Commission and Huangpu District Health Bureau, focusing on high-precision screening and innovative mobilization models [1]. - The project aims to provide a comprehensive management approach from prevention to diagnosis and treatment, ensuring zero payment for residents [1][2]. - The introduction of fecal gene testing technology positions Guangzhou at the forefront of national colorectal cancer screening efforts [1][2]. Group 2: Implementation and Impact - Since the launch of the colorectal cancer prevention project in 2015, Guangzhou has conducted 817,100 initial screenings, identifying 129,100 high-risk individuals with an early diagnosis rate of 90.65% and a cancer early-stage diagnosis rate of 41.28% [3]. - The project integrates community health services and specialized hospitals to facilitate early screening and follow-up care, enhancing the overall effectiveness of cancer prevention [3][4]. Group 3: Community Engagement and Education - The project includes various community activities, such as health consultations and educational performances, to raise awareness about cancer prevention and promote early screening [2][5]. - The use of the "Changtian" WeChat mini-program for risk assessment has increased participation among younger residents, indicating a shift in engagement strategies [6]. Group 4: Future Directions and Innovations - The project is exploring new screening models, including family member screenings and regional early screening centers, to address challenges in community mobilization and participation [5][6]. - The establishment of a comprehensive service system for screening, diagnosis, and treatment aims to ensure quality and efficiency in cancer care [7].