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马小丽教授:守正创新,古方新用直击抑郁症防治难题
Huan Qiu Wang· 2025-07-01 10:46
Core Viewpoint - The conference highlighted the clinical applications of traditional Chinese medicine (TCM) formulas Banxia Houpu Decoction and Zhizi Houpu Decoction in treating emotional disorders, particularly depression, showcasing their safety and effectiveness through innovative transformations into new treatments like Jieyu Chufan Capsules [1][3][4] Group 1: Clinical Applications - Banxia Houpu Decoction, originating from Zhang Zhongjing's "Jinkui Yaolue," is effective in treating depression and anxiety by improving sleep, regulating emotions, and alleviating physical symptoms [3] - Zhizi Houpu Decoction, from "Shanghan Zabing Lun," is used for insomnia and irritability, demonstrating clear efficacy in treating emotional disorders [3] Group 2: Innovative Developments - The Jieyu Chufan Capsules, developed from the foundational formulas, exhibit multi-channel effects and high safety, providing a new treatment option for depression and anxiety [3][4] - Research indicates that Jieyu Chufan Capsules can significantly reduce Hamilton Anxiety Scale (HAMA) scores in patients with specific emotional disorders, improving their overall condition without increasing adverse reactions [4] Group 3: Research Findings - Animal studies suggest that Jieyu Chufan Capsules may exert antidepressant effects by regulating levels of monoamine neurotransmitters in the central nervous system [4] - Clinical studies show that the adverse reaction rate of Jieyu Chufan Capsules is comparable to that of a placebo and significantly lower than that of fluoxetine, indicating good safety [4]