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做“足”功课,降低糖尿病并发症风险
Ke Ji Ri Bao· 2025-06-24 01:12
专家建议,预防糖尿病足,糖尿病患者每日需用38℃以下温水泡脚,擦干后检查趾间有无破损,穿 透气棉 袜与宽松鞋,并每年至少做一次足部血管神经专项检查。 国际糖尿病联盟最新数据显示,我国20—79岁糖尿病患者人数到2030年预计将突破1.64亿人。随着 糖尿病患病率的持续攀升,糖尿病足这一严重并发症的患病人数也呈逐年递增趋势。临床统计表明,我 国50岁以上糖尿病患者中,糖尿病足1年新发率达8.1%,总截肢率高达19.3%。 令人振奋的是,广州医科大学与中国科学院联合团队近期通过基因工程改造干细胞技术,实现实验 室环境下14天内糖尿病足伤口愈合率超96%,为众多患者带来希望。与此同时,抗生素骨水泥、脊髓电 刺激器植入术(SCS)、血管重建与修复等治疗技术也取得突破性进展,为糖尿病足的临床干预开辟了 新路径。 血糖失控渐进性破坏足部组织 "糖尿病是一种表现为血糖异常升高的代谢性疾病。糖尿病对双足的影响,本质是高血糖引发的'血 管—神经—免疫'三重打击。"天津医科大学第二医院手足显微外科副主任医师苗平指出,糖尿病足的发 生、发展背后是血糖失控对足部组织的渐进性破坏。 多项突破为解决临床难题带来希望 糖尿病足作为糖尿病最 ...
AirSculpt Technologies(AIRS) - 2024 Q4 - Earnings Call Transcript
2025-03-14 18:47
Financial Data and Key Metrics Changes - For Q4 2024, revenue totaled $39.2 million, a decline of 17.7% from Q4 2023, with case volume down 16.7% year-over-year [13][33] - Adjusted EBITDA was $1.9 million or 4.7% of revenue, compared to $10.1 million or 21.2% of revenue in the same quarter last year [16][38] - For the full year, revenues were $180.4 million, a decline of 7.9% from fiscal 2023, with adjusted EBITDA of $20.7 million and an adjusted EBITDA margin of 11.5% [18][39] Business Line Data and Key Metrics Changes - Same-store revenue declined 22.6% year-over-year in Q4 2024, reflecting challenges in the aesthetics market [13][33] - The average spend per procedure remained between $12,000 and $13,000, indicating a longer conversion time from leads to cases, increasing from approximately 45 days to closer to 60 days in the second half of 2024 [14][15] Market Data and Key Metrics Changes - The percentage of patients using financing for procedures was 50%, down from 53% in previous quarters, indicating a shift in consumer behavior [34] - The company operates in a $11 billion total addressable market in the U.S., highlighting significant growth potential despite current challenges [11] Company Strategy and Development Direction - The company aims to enhance its culture and align on a singular vision while improving its go-to-market strategy to drive consistent revenue growth [20][29] - Five key priorities include marketing to drive consumer interest, improving sales processes, introducing new services, enhancing customer experience, and leveraging technology [20][28] Management's Comments on Operating Environment and Future Outlook - Management acknowledged the challenging consumer backdrop affecting sales across the aesthetics space and emphasized the need for internal corrections [14][12] - The company expects Q1 2025 same-store sales performance to mirror Q4 2024 trends, with an anticipated sequential improvement as marketing spend increases [30][42] Other Important Information - The company has paused new center openings to focus on improving same-center performance and has amended its credit agreement to enhance investment flexibility [29][31] - Cash flow from operations for the year was $11.4 million, down from $24 million in fiscal 2023, with gross debt outstanding at $75.8 million [41] Q&A Session Summary Question: Can you provide more color on sequential growth expectations? - Management expects to see a similar seasonal trend with sequential improvement in same-store performance year-over-year, particularly in Q2 [51] Question: What are the liquidity improvement actions being taken? - The company drew down on its revolving credit facility to maintain marketing efforts while facing challenges in Q4 results [56] Question: How should we think about marketing spend versus customer acquisition cost (CAC)? - The elevated CAC was driven by lower case volumes and reduced lead volumes due to decreased marketing spend, but improvements in marketing strategy are expected to lower CAC in the future [62] Question: Can you elaborate on the cost savings program? - The company has executed a $3 million annual savings plan primarily through reductions in corporate headcount not aligned with the current strategy, with benefits expected to start in Q1 [67] Question: What specifics can you share about new marketing efforts? - The company is combining traditional paid search with new initiatives like online video and social marketing, focusing on a returns-based approach to optimize spending [72]