Core Insights - The Zibo Maternal and Child Health Hospital has established itself as a benchmark institution in the field of prenatal diagnosis, achieving an annual outpatient volume of 20,000 and reducing the birth defect rate in Zibo to 1.7% over 20 years [1][12] Group 1: Institutional Achievements - The center has been recognized as the Zibo Prenatal Screening and Diagnosis Quality Control Center and the Zibo Comprehensive Intervention Center for Birth Defects, contributing to a comprehensive three-tier prevention system covering pre-pregnancy, prenatal, and neonatal stages [1] - The center has served over 400,000 outpatient visits, providing critical support for families in Zibo and surrounding areas [1] Group 2: Technological Advancements - The center employs advanced technologies such as high-throughput sequencing capable of detecting millions of genetic loci and minimally invasive procedures like chorionic villus sampling [8] - It has developed a full-cycle diagnostic and intervention system that includes prenatal precision diagnosis, intrauterine minimally invasive interventions, and long-term follow-up management [13] Group 3: Impact on Birth Defects - Since participating in the "Government Livelihood Project" in 2021, the center has provided free screening services to over 70,000 pregnant women, achieving a 100% diagnosis and intervention rate for high-risk pregnancies [9] - The center has completed 11,948 prenatal diagnoses, identifying 807 cases of chromosomal abnormalities and 103 cases of single-gene diseases [9] Group 4: Community Engagement and Education - The center conducts regular training for medical personnel, averaging 300 participants annually, and promotes public awareness of prenatal health through community outreach programs [14] - It has successfully integrated social benefits with medical care, enhancing public awareness of healthy childbirth practices [15]