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创新助力全球抗疟事业 盖茨基金会合作项目成果显著
Huan Qiu Wang Zi Xun· 2025-08-20 16:22
Core Insights - The global malaria cases reached 263 million in 2023, resulting in approximately 600,000 deaths, with 80% of these being children under five years old [1] - China has been recognized as a "malaria-free country" by the World Health Organization since 2021, transitioning from a high-incidence area to a model for malaria elimination [1] Technological Innovations - The Gates Foundation highlights the challenges in global malaria control, including rising malaria cases and stagnation in resource investment, alongside increasing resistance of malaria parasites to artemisinin-based drugs [2] - A new "black box" mosquito monitoring device developed by a research team is designed to address outdoor mosquito transmission challenges, capturing and analyzing mosquito data in real-time [3] - Traditional wisdom is being leveraged to discover new mosquito repellent compounds, with a team identifying six high-activity molecules from over 60,000 compounds, showing promise for environmentally friendly solutions [4] Drug Development Breakthroughs - The ideal malaria drug should be low-dose, low-toxicity, and highly accessible, with a focus on developing single-dose treatments that maintain efficacy for extended periods [5] - Two promising candidate molecules have been identified that can provide 28 days of malaria protection with minimal risk of resistance [5] - The Gates Foundation supports the transition of innovative drugs from research to application, exemplified by a new artemisinin-based drug receiving WHO prequalification [6] Experience Sharing and Global Health Empowerment - China has developed a unique "1-3-7 model" for malaria elimination, which emphasizes rapid case reporting and control measures, and is being adapted for use in other countries [7] - A collaborative project in Tanzania has successfully implemented this model, benefiting approximately 300,000 people and significantly reducing malaria prevalence in intervention areas [8] - The global health landscape faces unprecedented challenges, and China's contributions in malaria control are increasingly significant, transitioning from a participant to a contributor in global health governance [8]