Core Insights - U.S. stocks exhibited mixed performance, with the Dow Jones index declining by over 50 points on Thursday [1] - Taysha Gene Therapies Inc received Breakthrough Therapy designation from the FDA for TSHA-102, leading to a significant share price increase of 50.4% to $4.78 [1] Company Highlights - Taysha Gene Therapies Inc (NASDAQ:TSHA) saw its price target raised from $8 to $10 by Needham analyst Gil Blum, maintaining a Buy rating [1] - Bakkt Holdings Inc (NYSE:BKKT) experienced a 37.2% increase in share price to $46.81 following the completion of its Loyalty Business sale [4] - Canaan Inc – ADR (NASDAQ:CAN) shares surged by 29.8% to $1.35 after announcing a significant sales order for Bitcoin mining machines [4] - Ondas Holdings Inc (NYSE:ONDS) gained 25.5% to $9.18 after securing an initial order of 500 Wasp drones for U.S. defense market distribution [4] - Fair Isaac Corp (NYSE:FICO) shares rose 19.6% to $1,811.61 after launching the FICO Mortgage Direct License Program [4] - AST SpaceMobile Inc (NASDAQ:ASTS) jumped 12.3% to $63.98 after completing final assembly and testing of its BlueBird 6 satellite [4] - Joby Aviation Inc (NYSE:JOBY) rose 9.3% to $17.72, reflecting positive market sentiment [4] - Applied Digital Corp (NASDAQ:APLD) shares increased by 7.7% to $26.93, with crypto-linked stocks trading higher amid a rise in Bitcoin [4]

Group 1 - AST SpaceMobile's stock experienced a significant increase following the announcement of a production and launch update for its BlueBird satellites [1] - The BlueBird 6 satellite has completed final assembly and testing, and is scheduled to be shipped to India on October 12 [1] - The company anticipates shipping its BlueBird 7 satellite soon after the BlueBird 6 [1] Group 2 - EchoStar's stock surged after the announcement of a spectrum sale to SpaceX valued at approximately $17 billion, which includes $8.5 billion in cash [2] - The sale is expected to enhance EchoStar's financial position and market presence in the satellite communications sector [2]