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EGFR/cMet双抗ADC TQB6411
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国产创新药持续出海 中国生物制药标志性授权交易落地在即
Core Viewpoint - The article highlights the significant potential for China National Pharmaceutical Group (China Biopharmaceutical) to expand its international revenue through out-licensing deals, with a major transaction expected to be announced soon [1] Group 1: Company Developments - China Biopharmaceutical has identified multiple assets with out-licensing potential and has received cooperation intentions from both leading multinational pharmaceutical companies and innovative drug firms [1] - The company aims to achieve at least one major out-licensing deal this year, which is expected to become a recurring source of revenue and profit starting in 2025 [1] - The company has a robust pipeline that includes various products such as PDE3/4, HER2 bispecific antibodies, and ADCs, which are positioned for potential out-licensing [1][3] Group 2: Market Context - The global pharmaceutical market has seen high commercial value for similar products, with recent transactions reaching unprecedented amounts, indicating strong demand for innovative drug technologies [2] - The ADC platform has become a focal point for multinational companies, with significant deals being reported, such as a $50 billion potential transaction involving EGFR-ADC products [2] - The domestic innovative drug sector has experienced a surge in out-licensing transactions, with 41 deals totaling $36.93 billion reported in the first quarter of 2025 alone, nearing the total for the entire year of 2023 [4] Group 3: Industry Trends - The number of active innovative drug pipelines in China has increased dramatically, positioning the country as a leader in global pharmaceutical innovation [4] - China Biopharmaceutical ranks second among Chinese pharmaceutical companies with 125 projects in development, surpassing several multinational corporations [4] - The ongoing trend of out-licensing reflects the growing recognition of China's drug innovation capabilities by multinational corporations, suggesting a sustained realization of value for domestic innovative drugs [4]
又一预告!中国生物制药重磅BD即将达成 中国创新药“Deepseek时刻”到来?
Xin Lang Cai Jing· 2025-06-12 04:43
Core Viewpoint - The Chinese innovative pharmaceutical sector is experiencing a significant moment, with multiple companies, including China Biologic Products, announcing major out-licensing deals and collaborations, indicating a strong trend towards internationalization and growth in the industry [1][2][6] Group 1: Company Developments - China Biologic Products announced at the Goldman Sachs Global Healthcare Conference that it expects at least one major out-licensing deal to be finalized this year, which is a key strategic goal for the company [2][3] - The company has identified several products with out-licensing potential, including PDE3/4, HER2 bispecific antibodies, and various ADCs, and has begun outreach to potential partners [3][4] - The stock price of China Biologic Products surged nearly 15% following the announcement of these developments, reflecting strong market interest [3] Group 2: Market Trends - The trend of out-licensing deals among Chinese innovative drug companies is gaining momentum, with several companies announcing significant transactions, such as 60.5 billion USD by 3SBio and 50 billion USD by CSPC [5][6] - In the first quarter of 2025, there were 41 out-licensing transactions in China, totaling 36.93 billion USD, indicating a rapid increase in activity compared to previous years [5] - The innovative drug sector in Hong Kong has seen substantial growth, with an ETF rising approximately 60% this year, driven by the performance of companies like 3SBio and CSPC [6] Group 3: Clinical Advancements - China Biologic Products has made significant progress in clinical trials, with its PDE3/4 inhibitor TQC3721 recently approved for Phase III trials for COPD, positioning it as a global leader in development [3][4] - The company has also received approvals for its HER2 bispecific ADC TQB2102 and is advancing multiple other projects in the ADC and bispecific antibody fields [4]