Core Points - LAVA Therapeutics announced that approximately 87% of its outstanding common shares were validly tendered in the tender offer by XOMA Royalty Corporation, satisfying the minimum tender condition [1] - The subsequent offering period for LAVA shareholders to tender their shares will expire on November 20, 2025, and shares tendered during this period cannot be withdrawn [2] - LAVA intends to voluntarily delist its common shares from Nasdaq, contingent upon the completion of the acquisition by XOMA Royalty [3] Company Overview - LAVA Therapeutics is a biopharmaceutical company focused on developing bispecific gamma delta T cell engagers using its proprietary Gammabody® platform, with partnerships with Johnson & Johnson and Pfizer for specific cancer treatments [4]

Core Viewpoint - LAVA Therapeutics N.V. is urging its shareholders to tender their shares in the ongoing acquisition offer from XOMA Royalty Corporation before the expiration deadline of November 12, 2025, to avoid potential risks associated with the failure of the transaction [1][3][12]. Group 1: Transaction Details - On August 4, 2025, LAVA and XOMA entered into a share purchase agreement, with XOMA extending its offer to purchase all outstanding common shares of LAVA until November 12, 2025 [2]. - The LAVA Board unanimously recommends that shareholders tender their shares to ensure the completion of the offer [3]. Group 2: Risks of Non-Completion - If the requisite percentage of shares is not tendered, the offer cannot be completed, which may lead to significant risks for shareholders, including potential liquidation and dissolution of LAVA [3][6]. - In the event of non-completion, LAVA's share price may decline, particularly if the current market price reflects expectations of the offer being completed [6]. Group 3: Share Tendering Process - Shareholders holding LAVA shares through brokers are advised to instruct their brokers to tender their shares promptly to meet processing deadlines [4][5]. - Those who have previously tendered their shares do not need to take any further action due to the extension of the offer [8]. Group 4: Company Overview - LAVA Therapeutics is a biopharmaceutical company focused on developing bispecific gamma delta T cell engagers using its proprietary Gammabody® platform, with partnerships including Johnson & Johnson and Pfizer [9].

Core Points - XOMA Royalty Corporation has extended its tender offer to purchase all outstanding shares of LAVA Therapeutics N.V. until October 17, 2025, with the acquisition expected to close in Q4 2025 [1][2] Group 1: Tender Offer Details - The tender offer includes a cash amount and a non-transferable contingent value right (CVR) per share, entitling shareholders to 75% of net proceeds from LAVA's partnered assets and any out-licensed or sold unpartnered programs [1] - LAVA shareholders who have already tendered their shares do not need to take further action due to the extension of the offer [3] - The closing of the offer is contingent upon the tender of at least 80% of LAVA's outstanding shares, adoption of certain resolutions by LAVA's shareholders, and other customary closing conditions [4] Group 2: Company Background - XOMA Royalty is a biotechnology royalty aggregator that acquires future economic rights associated with therapeutic candidates licensed to pharmaceutical companies, providing non-dilutive funding to sellers [5] - LAVA Therapeutics is a biopharmaceutical company focused on developing bispecific gamma delta T cell engagers using its proprietary Gammabody® platform, with partnerships with Johnson & Johnson and Pfizer [6][7]

Core Insights - LAVA Therapeutics has received a full waiver of a $5.1 million repayment obligation from the Netherlands Enterprise Agency, significantly strengthening its balance sheet [1][2] - The company is focusing on cost optimization initiatives to enhance operational efficiency and financial flexibility as part of its ongoing strategic review [2] Company Overview - LAVA Therapeutics N.V. is a clinical-stage immuno-oncology company that develops its proprietary Gammabody® platform, which includes bispecific gamma-delta T cell engagers aimed at treating solid tumors and hematologic malignancies [3][4] - The company utilizes engineered bispecific antibodies to selectively target and kill cancer cells by activating Vγ9Vδ2 T cell anti-tumor functions [3] Pipeline and Development - LAVA's pipeline includes three clinical-stage bispecific gamma-delta T cell engagers: LAVA 1266 targeting CD123+ cancers, PF-08046052 targeting EGFR, and JNJ-89853413 targeting hematological cancers [4] - The company also has preclinical programs in development [4]

Core Insights - LAVA Therapeutics is focusing on maximizing shareholder value in 2025 by evaluating strategic options while continuing patient enrollment in the Phase 1 study of LAVA-1266, a treatment for acute myeloid leukemia and myelodysplastic syndrome [2][3] Corporate Highlights - The Phase 1 trial of LAVA-1266 is designed to target CD123+ tumor cells for hematological malignancies, evaluating safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-tumor activity [3] - LAVA has partnered with Johnson & Johnson and Pfizer for additional programs, with ongoing Phase 1 trials targeting CD33 and EGFR respectively [4][5] - A restructuring plan was adopted to extend capital resources, resulting in a 30% reduction in workforce to support strategic evaluations and the LAVA-1266 study [4][10] Financial Results - As of December 31, 2024, LAVA reported a cash balance of $76.6 million, expected to fund operations into 2027 [4][10] - Revenue from contracts with customers increased to $5.0 million for Q4 2024, up from $0.4 million in Q4 2023, and $12.0 million for the year ended 2024, compared to $6.8 million in 2023 [10][11] - The net loss for Q4 2024 was $3.8 million, compared to a net loss of $6.4 million in Q4 2023, with a total net loss of $25.1 million for the year 2024, down from $41.9 million in 2023 [10][11] Pipeline Overview - LAVA's pipeline includes three clinical-stage bispecific gamma-delta T cell engagers: LAVA-1266 for CD123+ cancers, PF-08046052 for EGFR, and JNJ-89853413 for hematological cancers [15] - The ongoing studies involve dose escalation and expansion segments to evaluate safety and preliminary anti-tumor activity across various cancer types [5][15]

Core Insights - LAVA Therapeutics is focused on maximizing shareholder value in 2025 by evaluating strategic options while continuing patient enrollment in the Phase 1 study of LAVA-1266, a treatment for acute myeloid leukemia and myelodysplastic syndrome [2][5] - The company reported a cash balance of $76.6 million as of December 31, 2024, which is expected to fund operations into 2027 [5][9] Clinical Development Highlights - LAVA-1266 is currently in a Phase 1 trial targeting CD123+ tumor cells for hematological malignancies, evaluating safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-tumor activity [3][6] - The partnered program with Johnson & Johnson (JNJ-89853413) is also in a Phase 1 trial, targeting CD33 and gamma delta T cells, with a development milestone of $5 million received in Q4 2024 [4][5] - Pfizer's partnered program (PF08046052) is in a Phase 1 trial for solid tumors, with a clinical development milestone of $7 million received in Q1 2024 [5][9] Financial Performance - Revenue from contracts with customers increased to $5.0 million in Q4 2024 from $0.4 million in Q4 2023, and for the full year, revenue rose to $12.0 million from $6.8 million [9][10] - Research and development expenses for Q4 2024 were $8.6 million, up from $2.3 million in Q4 2023, primarily due to costs associated with the discontinuation of LAVA-1207 [9][10] - The net loss for Q4 2024 was $3.8 million, compared to a net loss of $6.4 million in Q4 2023, with a full-year net loss of $25.1 million compared to $41.9 million in 2023 [9][10] Workforce and Restructuring - The company adopted a restructuring plan in February 2025, resulting in a 30% reduction in workforce to extend capital resources and focus on strategic options and the Phase 1 study for LAVA-1266 [5][9]