Transaction Overview - BD will separate its Biosciences and Diagnostic Solutions business to BD shareholders and simultaneously merge SpinCo with a wholly owned subsidiary of Waters in a tax-efficient Reverse Morris Trust transaction valued at approximately $17.5 billion[65] - Expected pro forma ownership of 60.8% for Waters shareholders and 39.2% for BD shareholders[65] - BD to receive approximately $4 billion cash distribution via proceeds of SpinCo debt[65] - The transaction is expected to close around the end of the first quarter of calendar year 2026[65] Financial Highlights - Pro forma revenue for CY 2025E is approximately $6.5 billion[18] - Adjusted EBITDA for CY 2025E is approximately $2.0 billion[18] - R&D spending is approximately 10% of sales[18] - The transaction is expected to be EPS accretive in Year 1[36] - Expected revenue synergies of approximately $290 million by Year 5, with an EBITDA impact of $145 million[33, 61] - Expected cost synergies of approximately $200 million by Year 3[33, 61] - Approximately $345 million in total annualized adjusted EBITDA synergies are expected by Year 5[36, 61] Growth and Stability - The combined company will have a total addressable market (TAM) of approximately $40 billion with 5-7% market growth[19, 22] - Over 70% of revenue is annually recurring[19, 30] - Over 50% of instruments are replaced every 5-10 years[19, 30] - Expected sales growth in the near-to-mid-term is MSD-HSD (Mid-Single-Digit to High-Single-Digit)[33] - Adjusted operating margin expansion of approximately 500 bps is expected by 2030[33]

Group 1 - The 2025 CPHI World Pharmaceutical Raw Materials Exhibition in Shanghai was successfully held, featuring an unprecedented scale with 3600 participating companies and over 30,000 overseas buyers from 147 countries [1] - Pharma United Co., Ltd. showcased its innovative products at the exhibition, highlighting its leadership in the cleanroom industry [1][2] Group 2 - Pharma United's HPL (High-Pressure Laminate) board was presented, demonstrating its superior performance in pharmaceutical applications, including high strength, wear resistance, and antibacterial properties, which help reduce contamination risks [2][3] - The company’s modular cleanroom models showcased its capabilities in cleanroom construction, emphasizing a 70% reduction in construction time compared to traditional methods [3] Group 3 - The exhibition included interactive areas that enhanced engagement, such as a coffee station and a dart game zone, fostering a lively atmosphere for networking [4] - Pharma United has been actively participating in CPHI exhibitions since its establishment in 2006, building a strong industry reputation and resource network [4] - The event served as a platform for industry discussions on cutting-edge technologies and market trends, laying a foundation for future collaborations [4]

导读： 本 次采购申请总金额约15.3亿元，主要用于仪器设备，占比超99%（约15.2亿元），少量涉及图 书和电动机。以下是各校采购申请的汇总信息。 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我 们的推送。 第四届微课大赛参赛作品抢先看！ 报名咨询：魏老师 15011302316（微信同号） 赞助咨询：李先生 18513107388（微信同号） 在当今数字化教育浪潮中，微课以其短小精悍、主题明确、针对性强等特点，逐渐成为教育领 域中一种备受瞩目的教学资源形式。为了进一步推动教育创新，促进教师之间的经验交流与共 享， 中国分析测试协会高校分析测试分会已经联合 成功举办了 3 届微课大赛。大赛吸引了众 多教育工作者的积极参与，收到了来自全国各地的大量优秀作品。 第四届微课大赛已于 4月份正式启动！目前已收到来自23个院校的报名信息！ 登录官网立即报名 第四届微课大赛参赛日程及奖励！ ↓ 更多微课作品 ↓ 大赛赞助单位： 发 文 不 易 ， 请 帮 小 编 点 下 "❤️" | 版 权 ： 本 文 部 分 素 材 源 自 网 络 ， 版 权 归 原 作 ...

导读： 华谱科仪完成过亿元Pre-B轮融资，致力于推进国产液相色谱技术革新与应用，打破进口垄断局面。 特别提示 微信公众号机制调整，请点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 近日，国产色谱设备、软件和耗材全体系平台企业 华谱科仪（北京）科技有限公司（以下简称"华谱科仪"） 已完成过 亿元 Pr e -B轮融资，本轮融资由京国瑞基金和北工投资在管的北京高精尖基金共同领投，老股东弘晖基金、架桥资本 跟投 ，本轮所融资金将主要用于国内外销售渠道的进一步建设和下一代产品的开发。 长海资本持续担任公司融资的独 家财务顾问 。 自2 0 1 5年成立以来，华谱科仪已建立起HPLC（高效液相色谱仪）、UHPLC（超高效液相色谱仪）以及配套的软件和 对应耗材的一系列产品矩阵。目前公司自有品牌仪器在色谱主流应用市场保有量达到数千台。华谱科仪凭借成熟完备的 合规化软件系统与服务体系，在国产液相色谱领域构建起显著的竞争优势，是行业内为数不多可以成体量进入海关、质 检、药监等制标单位，以及药企、CRO企业等关键商业化客户的厂商。 在现有产品以外，华谱科仪还在不断地拓展产品矩阵，从 ...

Maravai LifeSciences (MRVI) Q1 2025 Earnings Call May 12, 2025 05:00 PM ET Company Participants Deb Hart - Head of Investor RelationsTrey Martin - CEOKevin Herde - Executive VP & CFODan Arias - Managing DirectorBecky Buzzeo - Executive VP & Chief Commercial OfficerBrandon Couillard - Managing Director Conference Call Participants Conor McNamara - Equity Research AnalystDan Leonard - Managing Director & Research AnalystTejas Savant - Executive Director & Senior Healthcare Equity AnalystMatthew Stanton - Anal ...

Financial Data and Key Metrics Changes - The company reported $47 million in revenue for Q1 2025, exceeding expectations and showing a growth of over $4 million from Q4 2024 [6][27] - GAAP net loss before noncontrolling interests was $53 million for Q1 2025, compared to a loss of $23 million in Q1 2024 [27] - Adjusted EBITDA was negative $11 million for Q1 2025, down from a positive $8 million in Q1 2024 [28] - Basic and diluted EPS for Q1 was a loss of $0.21 per share, compared to a loss of $0.09 per share in Q1 2024 [30] Business Line Data and Key Metrics Changes - The Nucleic Acid Production (NAP) segment generated $29 million in revenue for Q1 2025, an increase of $1 million from Q4 2024 [6] - The Biologics Safety Testing (BST) segment reported $18 million in revenue for Q1 2025, up $3 million from Q4 2024 and flat compared to Q1 2024 [6][35] - The adjusted EBITDA margin for the BST segment was 70%, indicating strong performance [35] Market Data and Key Metrics Changes - Revenue by customer type in Q1 was 29% from biopharma, 28% from life science and diagnostics, 6% from academia, 7% from CDMO, and 30% through distributors [7] - Revenue by geography was 62% from North America, 15% from EMEA, 15% from Asia Pacific, and 8% from China [7] Company Strategy and Development Direction - The company is focused on a return to growth strategy and building a diversified franchise as a life science tool provider and clinical partner [10] - The strategy includes vertical integration in the NAP segment to enhance quality, speed, and cost efficiency [8] - The company aims to expand its product and service portfolio to drive long-term sustainable growth [10] Management's Comments on Operating Environment and Future Outlook - Management acknowledged the challenges of transitioning from a COVID-driven revenue model to a more diversified business [39] - The company is closely monitoring trade dynamics and working to mitigate potential impacts from tariffs [39] - The cash position of $285 million is seen as sufficient to manage the reset period while focusing on long-term growth [40] Other Important Information - The company plans to publish its 2024 sustainability report, highlighting its commitment to sustainability and long-term strategic objectives [25] - The integration of recent acquisitions is progressing well, enhancing operational capabilities and supply chain control [32] Q&A Session Summary Question: Focus areas for new trials and reasons for discontinuation - Management noted that while preclinical programs were flat, clinical programs showed growth, indicating a focus on later-stage projects due to funding conservatism [44][46] Question: Drivers of incremental demand in the next 12-18 months - Incremental demand is expected from clinical progression, new business wins, and the transition from bulk reagent supply to comprehensive service offerings [48] Question: Opportunities for market share due to U.S. manufacturing - The company sees potential for market share growth as interest in U.S.-based manufacturing increases, particularly in the mRNA space [51][54] Question: Impact of U.S. policy changes on customer buying patterns - Customers are experiencing mixed impacts from government funding changes, with some securing long-term funding while others delay decisions [60] Question: Government work and exposure - The company has no direct government work currently, with past contracts fulfilled, but remains open to future opportunities [66] Question: Seasonality in BST revenue - Q1 is typically a high point for BST revenue, influenced by manufacturing cycles and strong performance in China [70][72]

Financial Data and Key Metrics Changes - The company reported Q1 revenue of $23.9 million, representing a 30% year-over-year increase, primarily driven by a 33% increase in the cell processing platform revenue [14][17] - GAAP gross margin for Q1 2025 was 63%, consistent with Q1 2024, while adjusted gross margin remained at 66% [14][15] - Adjusted EBITDA for Q1 2025 was $5.7 million, or 24% of revenue, compared to $2.6 million, or 14% of revenue in the prior year [17][18] Business Line Data and Key Metrics Changes - Cell processing revenue increased to $21.6 million, a 33% year-over-year increase and a 6% sequential increase from Q4 last year [6][7] - The biopreservation media (BPM) product line continues to be a significant driver, with 80% of BPM revenue coming from the top 20 customers [8][9] - Approximately 60% of BPM revenue comes from direct sales, with 40% from distribution channels [9] Market Data and Key Metrics Changes - The company estimates that its BPM products are used in at least 70% of relevant commercially sponsored cell and gene therapy (CGT) trials in the U.S., with a share of late-stage clinical trials exceeding 75% [10] - The company has a strong position in the market, with only homebrew formulations as meaningful alternatives to its offerings [11] Company Strategy and Development Direction - The company is focused on delivering leading solutions to the cell and gene therapy market and is committed to sustainable growth throughout 2025 [7][13] - The acquisition of Panthera CryoSolutions is aimed at expanding the biopreservation portfolio and enhancing scientific capabilities [13] - The company is optimistic about long-term industry fundamentals but acknowledges near-term uncertainties from factors like tariffs and NIH funding cuts [13] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in navigating potential headwinds with minimal impact on financial results [71] - The company reaffirmed its full-year revenue guidance of $95.5 million to $99 million, with growth led by the cell processing platform [14][19] Other Important Information - The company ended the quarter with over $100 million in cash, providing a solid foundation for growth initiatives [7] - Adjusted operating income for Q1 2025 was $900,000, compared to an adjusted operating loss of $2.4 million in Q1 2024 [17] Q&A Session Summary Question: Insights on clinical side demand trends - Management noted that clinical customers showed reasonable performance, with growth driven primarily by commercial customers [22][23] Question: Details on the Panthera acquisition - The acquisition was timed to leverage proven technology and aims to develop next-generation cryopreservation products [26][27] Question: Current status of pricing changes - Management indicated that they are more than halfway through pricing adjustments for key customers, with a gradual implementation over three years [33][34] Question: Impact of tariffs and NIH funding - Management assessed that they have limited exposure to tariffs and NIH funding cuts, with minimal impact expected on their cost of goods [39][40] Question: Future M&A pipeline and CapEx projects - The company is exploring small tuck-in acquisitions and has plans for significant CapEx projects, including facility expansions [46][47] Question: Potential for media swaps with Panthera products - Management indicated that switching costs for customers to change biopreservation media are significant, making it unlikely for existing commercial products to switch [52][54] Question: Ability to pass on tariff costs to customers - Management confirmed that they could implement surcharges for any material increases in costs due to tariffs [55][56]

Financial Data and Key Metrics Changes - The company reported Q1 revenue of $23.9 million, representing a 30% year-over-year increase, primarily driven by a 33% increase in the cell processing platform revenue [13][15] - GAAP gross margin for Q1 2025 was 63%, consistent with Q1 2024, while adjusted gross margin remained at 66% [13][14] - Adjusted EBITDA for Q1 2025 was $5.7 million, or 24% of revenue, compared to $2.6 million, or 14% of revenue in the prior year [15][16] Business Line Data and Key Metrics Changes - Cell processing revenue increased to $21.6 million, a 33% year-over-year increase and a 6% sequential increase from Q4 last year [6][15] - The biopreservation media (BPM) product line continues to be the primary driver of revenue, with top 20 customers accounting for approximately 80% of BPM revenue [6][7] - The company expects continued growth from commercial customers, with around 40% of BPM revenue coming from customers with approved commercial therapies [7][12] Market Data and Key Metrics Changes - Approximately 60% of BPM revenue comes from direct sales, while 40% is through distribution [7] - The company estimates its BPM products are used in at least 70% of relevant commercially sponsored cell and gene therapy trials in the U.S., with a share of late-stage clinical trials exceeding 75% [8][9] Company Strategy and Development Direction - The company is committed to delivering leading solutions to the cell and gene therapy market and has reaffirmed its full-year revenue guidance of $95.5 million to $99 million [12][13] - The acquisition of Panthera CryoSolutions is aimed at expanding the biopreservation portfolio and enhancing scientific capabilities, with a focus on developing next-generation cryopreservation products [12][26] - The company is actively monitoring potential near-term headwinds from tariffs and NIH funding cuts but does not expect any material impact on its financial outlook [12][39] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in navigating potential headwinds with minimal impact on financial results, emphasizing the strength of the balance sheet with over $100 million in cash [6][68] - The company remains optimistic about long-term industry fundamentals despite recognizing near-term uncertainties [12][68] Other Important Information - The company expects adjusted gross margin for the full year to be in the mid-60s, with a reduction in GAAP net loss and expansion in adjusted EBITDA margin due to higher expected revenue [18] - The company has a cash and marketable securities balance of $107.6 million as of March 31, 2025 [16] Q&A Session Summary Question: Insights on clinical side demand trends - Management noted that clinical customers buying directly showed reasonable performance, with growth driven primarily by commercial customers [21][22] Question: Rationale behind Panthera acquisition - The acquisition was timed to leverage proven technology and enhance the development of next-generation cryopreservation products [24][26] Question: Current status of pricing changes - Management indicated that they are more than halfway through pricing adjustments for key customers, with a gradual implementation over three years [31][32] Question: Impact of tariffs and NIH funding - Management assessed that they have limited exposure to tariffs and NIH funding cuts, with most products manufactured in the U.S. [37][39] Question: Future M&A pipeline - The company is exploring small tuck-in acquisitions similar to Panthera, with a strict filter criteria for potential targets [32][33] Question: Incremental OpEx from Panthera acquisition - Expected incremental OpEx from the Panthera acquisition is around $1 million for the remaining nine months of the year [60]

Core Insights - BioLife Solutions, Inc. reported a strong start to 2025 with a 33% year-over-year growth in cell processing revenue, reaching $21.6 million [1][2] - The company achieved a GAAP gross margin of 63% and a non-GAAP adjusted gross margin of 66% for Q1 2025, consistent with the same period in 2024 [5] - The net loss from continuing operations was reduced to $0.4 million in Q1 2025, compared to $3.2 million in Q1 2024, indicating improved financial performance [10][11] Financial Performance - Total revenue for Q1 2025 was $23.9 million, a 30% increase from $18.4 million in Q1 2024 [8] - Adjusted EBITDA for Q1 2025 was $5.7 million, representing 24% of revenue, up from $2.6 million or 14% of revenue in Q1 2024 [12] - The operating loss from continuing operations decreased to $1.2 million in Q1 2025 from $3.3 million in Q1 2024 [6][29] Business Highlights - The company processed 13 new U.S. FDA Master File cross references for its biopreservation media, bringing the total to 782 [7] - BioLife's biopreservation media is now embedded in 17 unique commercial cell and gene therapies, with expectations for further approvals and geographic expansions [7] - The acquisition of PanTHERA CryoSolutions was completed on April 4, 2025, enhancing BioLife's capabilities in the biopreservation market [7] Guidance and Outlook - BioLife Solutions affirmed its 2025 revenue guidance of $95.5 million to $99.0 million, reflecting a growth of 16% to 20% compared to 2024 [13] - The company anticipates maintaining gross margins in the low 60% range and adjusted gross margins in the mid-60% range for 2025 [13]

Waters (WAT) Q1 2025 Earnings Call May 06, 2025 08:00 AM ET Speaker0 Good morning. Call is being recorded. If you have any objections, please disconnect at this time. It is now my pleasure to turn the call over to mister Caspar Tudor, head of investor relations. Please go ahead, sir. Speaker1 Thank you, Leila, and good morning, everyone. Welcome to Walters Corporation's first quarter earnings call. Joining me today are doctor Udit Batra, our president and chief executive officer and Amol Chawwal, our senior ...