Core Viewpoint - Cervical cancer is a common malignant tumor among women, with significant global and national incidence and mortality rates in 2022 [1] Group 1: Incidence and Mortality - In 2022, there were 661,000 new cases of cervical cancer globally, with 348,000 deaths [1] - In China, the new cases and deaths were 151,000 and 56,000 respectively [1] Group 2: Causes of Cervical Cancer - Human Papillomavirus (HPV) infection is the primary cause of cervical cancer, with over 200 types identified, categorized into high-risk and low-risk types [2] - High-risk HPV types, particularly HPV16 and HPV18, are the most carcinogenic [2] - Risk factors include early sexual activity, multiple sexual partners, multiple pregnancies, smoking, and long-term use of oral contraceptives [2] Group 3: Prevention Measures - Health education is crucial for cervical cancer prevention, promoting awareness and healthy lifestyle choices [3] - There is a rising trend of early sexual behavior and high-risk sexual activities among young women in China [3] Group 4: HPV Vaccination - HPV vaccination is an effective preventive measure against cervical cancer, with five types of vaccines available in China [4] - It is recommended for high-risk women to receive the vaccine early [5] - Women with a history of HPV infection or cervical abnormalities can still receive the vaccine [6] - Pregnant or breastfeeding women should avoid vaccination [7] - The optimal age for vaccination is 9-26 years, especially for girls aged 9-14 [8] Group 5: Screening and Early Detection - Regular cervical cancer screening is essential for early detection and intervention [12] - The main screening methods are Liquid-based Cytology (TCT) and HPV DNA testing [12] - Women aged 21-65 should undergo regular screenings, with specific recommendations based on age [13] Group 6: Treatment Protocols - Standardized treatment is key for improving cure rates and survival for diagnosed precancerous lesions and cervical cancer [14] - Treatment options vary based on the severity of the condition, with a focus on surgical and chemoradiation therapies for advanced cases [14] - Regular follow-ups are necessary post-treatment to monitor health [14]