信达生物(01801)再涨超5%，截至发稿，涨5.56%，报90.1港元，成交额6.03亿港元。 海通国际认为，首付款与里程碑款将强化信达的财务安全垫，销售分成使其长期受益于全球市场增长。 合作聚焦的肿瘤与免疫领域，可与信达现有核心管线，如IBI363(PD1/IL2)、IBI343(CLDN18.2ADC)等 形成协同，提升整体竞争力。高盛则称，考虑到当前市场隐含的加权平均资本成本(12%)较高，认为其 目前股价被低估；予该股"买入"评级；基于风险调整后、现金流量折现法，予目标价102.85港元。 消息面上，信达生物日前宣布与礼来制药达成第七次战略合作，双方将携手推进肿瘤及免疫领域创新药 物的全球研发。根据协议条款，信达生物将直接获得3.5亿美元首付款。基于研发、监管及商业化等多 个节点的达成，信达后续还有资格获得总额最高约85亿美元的里程碑付款，并获得相关产品在大中华区 以外市场的梯度销售分成。据悉，在昨日举行的业务进展更新电话会上，信达生物管理层针对此次高额 交易的底层逻辑、资金流向以及公司全球化战略进行了详细披露。管理层表示，3.5亿美元的首付款将 很快到账，可有效覆盖公司未来的海外临床投入。 ...

Core Viewpoint - CITIC Securities maintains a "Buy" rating for Innovent Biologics (01801), projecting revenues of 11.806 billion yuan, 15.382 billion yuan, and 21.092 billion yuan for 2025-2027, respectively, with a DCF valuation indicating a fair market value of 221.5 billion HKD and a target price of 129.61 HKD [1] Group 1 - The company has established a significant presence in the oncology sector, with high-value clinical products expected to enhance revenue and reduce marginal costs [1] - In non-oncology sectors, the company has made extensive investments in metabolism, autoimmune diseases, and ophthalmology, with competitive and advanced products both launched and in development [1] Group 2 - On October 22, Innovent Biologics entered a global strategic partnership with Takeda Pharmaceutical, which will pay 1.2 billion USD upfront, including a strategic equity investment of 100 million USD at a subscription price of 112.56 HKD per share, representing a 20% premium over the weighted average share price of the past 30 trading days [1] - The total value of the collaboration could reach 11.4 billion USD, with Innovent Biologics and Takeda jointly developing IBI363 (PD-1/IL-2α-bias) [1] - Innovent Biologics granted Takeda exclusive rights for IBI343 (CLDN18.2ADC) outside Greater China and exclusive options for IBI3001 (EGFR/B7H3ADC) outside Greater China [1]