Financial Data and Key Metrics Changes - In Q4 2025, RxSight reported sales of $32.6 million, a decrease of 19% year-over-year due to lower LDD sales, with LDD placements dropping from 83 units to 25 units globally [5][6] - Full year 2025 sales totaled $134.5 million, reflecting a 4% increase year-over-year, despite a 48% decrease in LDD revenue, which was partially offset by a 12% increase in LAL sales [8][9] - The gross profit margin for 2025 was 76.6%, up from 70.7% in 2024, driven by a higher mix of LAL revenue [9] - The company reported a net loss of $38.9 million for 2025, compared to a net loss of $27.5 million in 2024 [9] Business Line Data and Key Metrics Changes - LDD revenue in Q4 2025 was $3 million, down from $11 million in the same period last year, while LAL sales accounted for 86% of total company sales, up from 71% year-over-year [6][7] - The company sold 28,611 LALs in Q4 2025, a 2% decrease from the previous year but a 10% increase sequentially [7] Market Data and Key Metrics Changes - The company anticipates a year-over-year decline in revenue for 2026, with guidance set at $120 million to $135 million, primarily due to lower LDD sales [10] - The international market is expected to contribute modestly to sales in 2026, with a focus on building relationships with key opinion leaders and collecting clinical data for future growth [11][19] Company Strategy and Development Direction - RxSight aims to improve utilization within its existing installed base through targeted practice engagement and education initiatives, while expanding access to technology in a measured way [16][20] - The company is focused on advancing its LAL technology and has received approximately 20 FDA approvals in support of product development over the past five years [18][19] - RxSight is building a foundation for long-term success in international markets, with a focus on developing key opinion leaders and clinical data [19][20] Management's Comments on Operating Environment and Future Outlook - Management acknowledged that 2025 financial results were below expectations but highlighted meaningful progress in advancing LAL technology and improving clinical outcomes [13][14] - The company is optimistic about the potential for growth in the second half of 2026 as commercial initiatives begin to gain traction [10][22] Other Important Information - The company ended 2025 with no debt and approximately $228 million in cash equivalents and short-term investments [9] - Gross margin guidance for 2026 is set at 70%-72%, reflecting a prudent view due to the sell-through of higher-cost inventory [11][12] Q&A Session Summary Question: What are the underlying health trends for LALs and LDDs in 2026? - Management noted an uptick in Q4 2025 and hopes this trend continues into 2026, with guidance reflecting these potential improvements [24][25] Question: What is the expected decline in LDD placements for 2026? - The company expects a slight acceleration in LDD placements, with Q1 anticipated to be the lowest quarter [30][31] Question: How long will manufacturing variances impact gross margin? - Management indicated that the impact of higher-cost inventory will be felt throughout 2026, but they expect improvements as the year progresses [34][37] Question: What is the competitive landscape for 2026? - Management is monitoring the competitive environment closely, noting that new product launches tend to be episodic and transient [45][46] Question: What is the go-to-market strategy for international expansion? - The company is focused on developing key opinion leaders and clinical data in international markets, leveraging learnings from North America [64][66]

Financial Data and Key Metrics Changes - In Q4 2025, RxSight reported sales of $32.6 million, a decrease of 19% year-over-year due to lower LDD sales, with LDD revenue contributing only $3 million compared to $11 million in the previous year [5][8] - Full year 2025 sales totaled $134.5 million, reflecting a 4% increase year-over-year, despite a 48% decrease in LDD revenue, which was partially offset by a 12% increase in LAL sales [8][9] - The gross profit margin for 2025 was 76.6%, up from 70.7% in 2024, primarily driven by a higher mix of LAL revenue [9] - The company reported a net loss of $38.9 million for 2025, compared to a net loss of $27.5 million in 2024 [9] Business Line Data and Key Metrics Changes - LDD sales saw a significant decline, with only 25 units sold in Q4 2025 compared to 83 units in the same period last year [5] - LAL sales were 28,611 units in Q4 2025, down 2% year-over-year but up 10% sequentially, accounting for 86% of total company sales, an increase from 71% in the previous year [6] - The gross margin for LALs improved to 77.5% in Q4 2025, compared to 71.6% in the year-ago period [6] Market Data and Key Metrics Changes - The company anticipates a relatively small contribution from international sales in 2026, focusing on building relationships with key opinion leaders and collecting clinical data for future growth [11] - The premium IOL market is expected to continue growing, driven by younger demographics seeking cataract surgery and a preference for high-quality vision [52] Company Strategy and Development Direction - RxSight aims to improve utilization within its existing installed base through targeted practice engagement and education initiatives, while expanding access to technology through disciplined LDD placements [15][16] - The company is committed to advancing its LAL technology and has received approximately 20 FDA approvals in support of product development over the past five years [18] - RxSight is focusing on international expansion, particularly in Europe, Asia, and Australia, to build a foundation for long-term success [19] Management's Comments on Operating Environment and Future Outlook - Management acknowledged that 2025 financial results were below expectations but highlighted meaningful progress in advancing LAL technology and improving clinical outcomes [13] - The company is optimistic about the potential for growth in 2026, with expectations for a rebound in sales in the second half of the year as commercial initiatives gain traction [10][21] - Management remains realistic about the challenges ahead but is focused on delivering consistent performance over time [20] Other Important Information - The company ended 2025 with no debt and approximately $228 million in cash equivalents and short-term investments [10] - Full-year revenue guidance for 2026 is set at $120 million to $135 million, implying a year-over-year decline at the midpoint of the range [10] Q&A Session Summary Question: What is the underlying health of the market for LALs and LDDs in 2026? - Management noted an uptick in Q4 2025 and hopes this trend continues into 2026, with guidance reflecting these potential improvements [24][25] Question: What are the assumptions for LDD placements and LAL growth in 2026? - The company expects LDD placements to slightly accelerate from the 2025 exit rate, with LAL growth anticipated in the low single-digit range [31][32] Question: How long will manufacturing variances impact gross margins? - Management indicated that they expect to work through lower-cost inventory over the course of 2026, with gross margins stabilizing in the second half of the year [34][37] Question: What is the competitive environment like for 2026? - Management is monitoring the competitive landscape, noting that while new product launches may occur, they tend to be transient and lead to a return to baseline over time [45][46] Question: What is the go-to-market strategy for international expansion? - The company is focused on developing key opinion leaders and clinical data in international markets, leveraging learnings from North America [64][66]