Core Insights - Alpha Teknova, Inc. reported total revenue of $10.5 million for Q3 2025, reflecting a 9% increase from $9.6 million in Q3 2024, marking five consecutive quarters of year-over-year revenue growth [1][6][9] - The company reaffirms its 2025 revenue guidance, expecting total revenue between $39 million and $42 million [1][12] Financial Performance - Revenue Breakdown: - Lab Essentials revenue was $8.3 million, up 16% from $7.2 million in Q3 2024 - Clinical Solutions revenue was $1.7 million, down 13% from $2.0 million in Q3 2024 [4][6] - Gross profit for Q3 2025 was $3.2 million, with a gross margin of 30.7%, significantly improved from $0.1 million and 0.9% in Q3 2024 [7] - Operating expenses decreased to $7.2 million in Q3 2025 from $7.5 million in Q3 2024, primarily due to reduced general and administrative spending [8] Cash Flow and Losses - Net loss for Q3 2025 was $4.3 million, or negative $0.08 per diluted share, an improvement from a net loss of $7.6 million, or negative $0.15 per diluted share, in Q3 2024 [10][22] - Adjusted EBITDA for Q3 2025 was negative $1.6 million, an improvement from negative $5.0 million in Q3 2024 [11][27] - Free Cash Outflow remained consistent at $2.4 million for both Q3 2025 and Q3 2024 [11][27] Balance Sheet Highlights - As of September 30, 2025, total cash and short-term investments were $22.1 million, with total borrowings of $13.2 million [9][23] - Total assets decreased to $107.6 million from $118.8 million as of December 31, 2024 [24] Market Position and Outlook - The company continues to see growth in its Clinical Solutions customer base, which, along with a diverse product portfolio, positions it for sustainable growth [2] - Teknova anticipates Free Cash Outflow of less than $12 million for the fiscal year 2025 [12]

Financial Data and Key Metrics Changes - Revenue for Q2 2025 was $10.3 million, a 7% increase from $9.6 million in Q2 2024, marking the fourth consecutive quarter of year-over-year growth [13][19] - Adjusted EBITDA improved to negative $800,000, the best quarterly result since going public in mid-2021, compared to negative $2.6 million in Q2 2024 [8][18] - Gross profit increased to $4 million with a gross margin of 38.7%, up from 29.2% in Q2 2024, driven by manufacturing efficiency gains [16][17] Business Line Data and Key Metrics Changes - Lab Essentials revenue was $7.8 million, a 2% increase from $7.6 million in Q2 2024, attributed to an increased number of customers [14] - Clinical Solutions revenue rose to $2.1 million, a 32% increase from $1.6 million in Q2 2024, also due to an increased number of customers [15][16] Market Data and Key Metrics Changes - Revenue from catalog products, which represents about 60% of annual revenue, grew in the low double digits year-over-year, aligning with historical growth rates from 2009 to 2019 [9][10] - The growth in catalog products was driven by key accounts in large pharma and life science tools, indicating above-market growth rates [10] Company Strategy and Development Direction - The company aims to be a leader in essential research reagents and to support emerging therapeutic developers through custom research and clinical grade reagents [9][12] - Inorganic growth opportunities are being pursued, including collaborations and acquisitions to enhance product offerings and operational scale [12][32] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the long-term outlook for end markets, despite challenges faced by small to mid-sized biotech customers [11][24] - The company reiterated its 2025 total revenue guidance of $39 million to $42 million, expecting continued growth in catalog products while custom products may see lower growth due to macroeconomic conditions [19][20] Other Important Information - The company reduced its headcount by about 40% from its peak, cutting annual operating expenses by approximately $18 million over the past three years [6] - Free cash flow for Q2 2025 was negative $2.3 million, an improvement from negative $3 million in Q2 2024 [18] Q&A Session Summary Question: How has the company managed through headwinds in the biotech funding landscape? - Management noted that while early-stage small to mid-sized biotech companies are struggling, the company has balanced losses with expected spending from larger companies and later-stage therapies [26][27][30] Question: Can you elaborate on the inorganic opportunities and gaps in the product portfolio? - The company is focusing on collaborations with smaller companies and potential acquisitions to fill gaps in upstream products like cell culture media and transfection reagents [31][32] Question: How is the RUO Plus initiative trending? - The initiative is performing as anticipated, providing flexibility for customers transitioning to clinical applications [36] Question: What are the expectations for Clinical Solutions revenue patterns? - Management indicated that revenue in Clinical Solutions can be lumpy, with no significant large orders affecting Q2 results, and that the business is currently in a normal range [38][75] Question: What are the key factors driving customer spending decisions in the current environment? - Customers are looking for predictability and stability, with recent positive engagement suggesting potential recovery in spending [50][51] Question: How has the company's sales force and online presence evolved? - The company has shifted from a reactive to a proactive approach in attracting new customers, contributing to growth despite macroeconomic challenges [56][59] Question: What are the expectations for gross margins in the second half of the year? - Management expects gross margins to remain lower than Q2 but anticipates continued improvements in efficiency and potential upside in the long term [61][66]

Financial Performance - Q2 2025 - Total revenue for Q2 2025 increased by 7% year-over-year, reaching $103 million[20] - Clinical Solutions revenue increased significantly by 32% compared to Q2 2024[21] - Gross margin improved from 292% in Q2 2024 to 387% in Q2 2025[23] - Adjusted EBITDA improved from a loss of $26 million in Q2 2024 to a loss of $08 million in Q2 2025[26] - Free cash flow improved from a negative $30 million in Q2 2024 to a negative $23 million in Q2 2025[28] Revenue Breakdown - 2024 - Catalog products accounted for approximately 60% of total revenue in 2024[14, 15] - Custom products represented about 35% of total revenue in 2024, with biopharma contributing 70% of custom revenue and 25% of total revenue[14, 15] - Other revenue, including services and shipping, made up roughly 5% of total revenue in 2024[14, 15] Customer Migration and Spending - Customers purchasing GMP reagents spent 44 times more annually compared to catalog-only customers in 2024[17] - 58% of 2024 revenue came from custom and/or clinical accounts[17] - 27% of 2024 revenue was generated from Cell and Gene Therapy (CGT) customers[17] 2025 Outlook - The company estimates total revenue between $39 million and $42 million, representing a 7% year-over-year increase at the midpoint[41] - The company is targeting a free cash outflow of less than $12 million for 2025[41] - The company estimates an annualized revenue range of $50 million to $55 million to achieve Adjusted EBITDA break-even[41]

Financial Performance - Q1 2025 - Total revenue increased by 5% year-over-year, from $9.3 million in Q1 2024 to $9.8 million in Q1 2025[23] - Lab Essentials revenue increased by 12% compared to the same period last year[23] - Clinical Solutions revenue decreased by 32% compared to the same period last year[23] - Gross margin increased from 23.8% in Q1 2024 to 30.7% in Q1 2025[25] - Total Operating Expenses (OpEx) decreased from $10.2 million in Q1 2024 to $8.0 million in Q1 2025, or $8.9 million excluding non-recurring workforce reduction expenses[26] - Adjusted EBITDA improved from a loss of $3.8 million in Q1 2024 to a loss of $2.5 million in Q1 2025[28] - Free Cash Flow improved from a loss of $6.7 million in Q1 2024 to a loss of $4.3 million in Q1 2025[32] Revenue Breakdown - 2024 - Catalog products accounted for approximately 60% of total revenue in 2024[14] - Custom products accounted for approximately 35% of total revenue in 2024, with Biopharma representing 70% of Custom Revenue and 25% of Total Revenue[14, 15] - Other revenue, including services and shipping, accounted for approximately 5% of total revenue in 2024[14] 2025 Outlook - The company estimates total revenue between $39 million and $42 million, representing a 7% year-over-year growth at the midpoint[44] - The company is targeting a free cash outflow of less than $12 million for 2025[44] - The company estimates an annualized revenue range of $50 million to $55 million to achieve Adjusted EBITDA break-even[44]

Table of Contents As filed with the Securities and Exchange Commission on August 23, 2024 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ALPHA TEKNOVA, INC. (Exact name of Registrant as specified in its charter) (State or other jurisdiction of incorporation or organization) Delaware 8731 94-3368109 (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identification Number) 245 ...