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Nature子刊:何川团队开发RNA修饰测序新方法——LIME-seq,可用于癌症早筛
生物世界· 2025-07-09 04:02
编辑丨王多鱼 排版丨水成文 循环游离 RNA (cfRNA) 是一类存在于血液中的短片段 RNA,被认为来自 机体细胞凋亡、组织更新或外泌体释放。然而,cfRNA 易被 RNA 酶降解、含量低、 片段短,长期以来它并不被视为液体活检的理想材料。 2025 年 7 月 8 日, 芝加哥大学 何川 教授团队、 香港科技大学 张理升 教授团队等 ( 芝加哥大学博士生 鞠成威 为第一作者) 在 Nature Biotechnology 期刊 发表了题为: Modifications of microbiome-derived cell-free RNA in plasma discriminates colorectal cancer samples 的研究论文。 其中,微生物组来源的 cfRNA 中的 RNA 修饰模式能准确反映宿主微生物群的活动,研究团队在结直肠癌患者和 非癌对照者血浆样本中进行了 LIME-seq 分 析,结果显示, 结直肠癌患者血浆中多种微生物来源的 cfRNA 甲基化水平显著升高,能够精准区分癌症患者与非癌个体。此外,研究团队在胰腺癌患者样本中 观察到了同样的 微生物来源的 cfRNA 甲基 ...
Martin Marietta Appoints Michael J. Petro as Chief Financial Officer
Globenewswire· 2025-07-08 11:30
RALEIGH, N.C., July 08, 2025 (GLOBE NEWSWIRE) -- Martin Marietta Materials, Inc. (NYSE: MLM) (“Martin Marietta” or the “Company”), a leading national supplier of aggregates and heavy building materials, today announced the appointment of Michael J. Petro as Senior Vice President and Chief Financial Officer, effective immediately. Robert J. Cardin, who has been serving as the Company’s interim CFO since April 2025, will continue in his role as Senior Vice President, Controller and Chief Accounting Officer. M ...
俄公布国家航天项目计划
Huan Qiu Wang Zi Xun· 2025-06-29 23:31
来源:环球时报 在日地关系研究领域,俄罗斯科学院提出"共振(Rezonans)"和"拱形(Arka)"项目,将分别发射研究 地球磁层和太阳日冕的航天器。克拉斯尼科夫说,这些航天器获取的数据,将与正在伊尔库茨克郊区建 设的俄科院西伯利亚分院日地物理研究所的地面太阳观测望远镜协同处理。他说:"全球科学界都依赖 俄罗斯在太空飞行对生物体影响方面的研究成果。这个方向上,科学家们计划发射两个载有动物的'生 物-М(Bion-М)'航天器。"这些项目旨在深入研究太空飞行对人体的影响,为极地轨道俄罗斯新空间 站及未来人类登陆月球和火星做准备。 克拉斯尼科夫说,月球计划资金将于今年开始投入。此前俄罗斯国家航天集团表示,该集团正与政府完 成航天战略计划修订工作,更新后的战略将在最终完善和俄罗斯总统批准后于2026年生效。据专家估 算,该国家项目的实施要求在未来3年拨款超1万亿卢布,2036年前投入约4.5万亿卢布。 科学航天意义重大 5月28日,俄罗斯科学院院长根纳季·克拉斯尼科夫出席莫斯科俄罗斯科学院全体会议。 探索宇宙奥秘 5月28日,俄罗斯科学院院长根纳季·克拉斯尼科夫在俄科院全体会议上公布将被纳入新国家项目的"航 天发 ...
中金 | 精品数据 • 月度上新:汽车智能化、铝、建材、电影
中金点睛· 2025-06-06 07:25
中金点睛"精品数据上新"栏目将带您回顾近期上新的数据看板。 01 汽车智能化数据 聚焦智能感知、智能决策、智能座舱三大板块,涵盖出货量、搭载量、渗透率、国产化水 平等关键指标,多维度展现市场趋势。 ➡【中金科技】汽车智能化数据 图: 毫米波雷达总体出货量 数据来源:高工智能汽车,中金公司研究部 02 铝行业观察 周度跟踪价格、库存、产量、开工率、现金利润及各项成本等核心指标的数据动态。 ➡【中金有色】铝行业观察 图: 铝土矿海内外价格 数据来源:亚洲金属网,中金公司研究部 03 建材行业高频数据追踪 高频追踪水泥、玻璃、玻纤细分市场的供需状况及价格走势,核心指标一键速览。 ➡【中金基材】建材行业高频数据追踪 图:全国水泥出货率 数据来源:卓创资讯,中金公司研究部 注:2025年数据截至日期为2025年6月1日 04 电影行业数据库 覆盖电影票房和电影渠道两大板块,精选票房、影院数、出票量、影投票房市占率等月度 指标。 ➡【中金传媒】电影行业数据库 图:分城市 月度票房 数据来源:艺恩,中金公司研究部 法律声明 更多特色数据,欢迎登录 中金点睛一站式数字化投研平台 ...
Why M/A-Com (MTSI) is a Top Growth Stock for the Long-Term
ZACKS· 2025-05-28 14:50
Core Insights - Zacks Premium offers various tools to help investors make informed decisions and invest confidently in the stock market [1][2] Zacks Style Scores - The Zacks Style Scores are indicators designed to assist investors in selecting stocks with the highest potential to outperform the market within 30 days, rated from A to F based on value, growth, and momentum [3][4][5][6][7] Value Score - The Value Style Score focuses on identifying undervalued stocks by analyzing financial ratios such as P/E, PEG, Price/Sales, and Price/Cash Flow [4] Growth Score - The Growth Style Score evaluates a company's future prospects by examining projected and historical earnings, sales, and cash flow to identify stocks with sustainable growth [5] Momentum Score - The Momentum Style Score helps investors capitalize on price trends by assessing factors like one-week price changes and monthly earnings estimate changes [6] VGM Score - The VGM Score combines the Value, Growth, and Momentum Scores, providing a comprehensive indicator for investors seeking stocks with attractive value, strong growth forecasts, and promising momentum [7] Zacks Rank - The Zacks Rank is a proprietary stock-rating model that leverages earnings estimate revisions to guide investors in building successful portfolios, with 1 (Strong Buy) stocks achieving an average annual return of +25.41% since 1988, significantly outperforming the S&P 500 [8][9] Stock Selection Strategy - Investors are encouraged to select stocks with a Zacks Rank of 1 or 2 and Style Scores of A or B to maximize potential upside, while those with lower ranks should also have strong Style Scores to mitigate risks [10][11] Company Spotlight: M/A-Com Technology Solutions Holdings, Inc. (MTSI) - MTSI is a provider of power analog semiconductor solutions, focusing on RF, microwave, and millimeter wave devices for various applications [12] - MTSI holds a Zacks Rank of 3 (Hold) with a VGM Score of B and a Growth Style Score of B, indicating a forecasted year-over-year earnings growth of 35.2% for the current fiscal year [12][13] - Recent upward revisions in earnings estimates by six analysts and an increase in the Zacks Consensus Estimate to $3.46 per share further enhance MTSI's attractiveness to growth investors [13]
一年测试超30款游戏,这家SLG大厂却变得保守了
3 6 Ke· 2025-05-22 11:27
IGG在经历大起大落之后似乎变得保守了。 去年IGG摆脱了自身的经营困境。公司营收超过57亿港元(约52亿人民币),同比增长9%,同时利润也增长697%达到5.8亿港元,相较于前年的亏损改善 了不少。不过IGG的优势依然在逐渐衰减。在Sensor Tower的发行商全球收入榜单上,此前IGG保持在15名上下,近两个月则掉至20多名的位置。IGG会感 到焦虑也在所难免。 现在IGG保持着每年30款左右的新品测试节奏。从产品类型来看,IGG对「创新」的看法发生了一些变化。可以发现,相较于之前女性向的《时光公 主》、狩猎共斗的《Yeager》等类型,近两年IGG的测试产品重新聚焦到SLG品类,收敛了想要突破小众赛道的想法。 新品研发依然坚持要有所创新,不过现在IGG也不希望离舒适圈太远了。 盯着市场爆款测试新品,过半都是SLG 前两年我们介绍过IGG在半年内测试了至少16款游戏,其中过半都是SLG产品。近一年来IGG依然维持着相近的节奏,并且仍然把筹码压在SLG品类上。 今年IGG在投资者电话会议中提到,接下来公司会有3款重磅产品,依照看好程度来排序的话,依次是SLG《Project PSS》、休闲社交《Tycoo ...
Uber Introduces Its Own Version of Prime Day: Uber One Member Days
CNET· 2025-05-14 15:11
If you're an Uber One member, you'll be able to take advantage of a massive new promo. The first Uber One Member Days event will run from Friday, May 16, to Friday, May 23, to coincide with Memorial Day sales on other tech shopping platforms. Uber One Member Days is structured very similarly to Amazon's various Prime Day sales -- paying members will have access to rotating benefits over the course of the event, timed with Memorial Day, compounded with the usual perks of an Uber One membership. Different rid ...
Tower Semiconductor(TSEM) - 2025 Q1 - Earnings Call Transcript
2025-05-14 15:00
Tower Semiconductor (TSEM) Q1 2025 Earnings Call May 14, 2025 10:00 AM ET Speaker0 Good day, and thank you for standing by. Welcome to the Tower Semiconductor First Quarter twenty twenty five Earnings Conference Call. At this time, all participants are in a listen only mode. After the speakers' presentation, there will be a question and answer speakers' there'll a Please be advised that today's conference is being recorded. I would now like to hand the conference over to your first speaker today, Ms. Noit L ...
Sky Quarry Signs LOI with R & R Solutions to Explore Expansion of Southwest Operations and Accelerate Market Deployment
Globenewswire· 2025-05-08 11:45
Core Viewpoint - Sky Quarry Inc. has signed a non-binding Letter of Intent with R & R Solutions Inc. to expand its waste-to-energy facilities and enhance revenue opportunities in the Southwest [1][4] Group 1: Partnership and Strategic Expansion - The partnership will focus on deploying Sky Quarry's proprietary equipment and processes at R & R Solutions' site in Albuquerque, New Mexico [2] - This collaboration aims to produce high-value byproducts such as asphalt-coated limestone, sand, granules, bitumen, and structural-grade ground shingles for various applications [2][3] - The partnership is seen as a strategic step for both companies, with R & R Solutions leveraging its experience in responsible recycling practices [4] Group 2: Revenue Generation and Processing Capacity - Sky Quarry expects to generate revenue from both accepting asphalt shingle waste and selling recovered byproducts [3] - The New Mexico site is estimated to process approximately 100,000 tons of asphalt shingle waste annually, potentially generating significant revenue from collection fees and sales of recycled materials [3] - The feedstock could yield up to 150,000 barrels of oil when fully refined, representing additional revenue potential [3] Group 3: Operational Efficiency and Market Position - The Albuquerque region is strategically located near Sky Quarry's PR Spring facility in Utah, which will serve as a hub for hydrocarbon extraction [4] - The integration of operations across both sites is expected to accelerate deployment, reduce capital intensity, and improve supply chain logistics for recovered oil products [4] - This collaboration is anticipated to drive stronger margins and long-term value for both companies [4]
Loma Negra pania Industrial Argentina Sociedad Anonima(LOMA) - 2025 Q1 - Earnings Call Transcript
2025-05-07 15:02
Loma Negra (LOMA) Q1 2025 Earnings Call May 07, 2025 10:00 AM ET Company Participants Diego Jalón - IR ManagerSergio Faifman - Vice-President of Board & CEOMarcos Isabelino Gradin - Chief Financial OfficerAlejandra Obregón Martínez - Vice President Equity ResearchDaniel Rojas Vielman - Vice President Conference Call Participants Marcelo Furlan Palhares - Equity Research Analyst Operator Good morning and welcome to the Loma Negra First Quarter twenty twenty five Conference Call and Webcast. All participants ...