Core Insights - The 2025 liquid chromatography-mass spectrometry (LC-MS) market is experiencing multiple changes, reflecting a shift from expansion to a competitive phase as indicated by a slight decline in total procurement numbers and amounts [1][3][25] Market Overview - The total number of units procured in 2025 reached 961, with a total procurement amount of 2.976 billion yuan, showing a slight decrease compared to the previous year [3] - Factors contributing to this contraction include adjustments in fiscal spending and procurement rhythms, as well as the growth of the after-sales service market and second-hand equipment leasing models [3] Competitive Landscape - A total of 37 mass spectrometer companies participated in the market, indicating an evolving competitive landscape [5] - Domestic brands have seen a significant increase in market share, rising from 11% to 17% year-on-year, driven by policy support and improved performance [7][8] Application and Regional Demand - The primary demand for LC-MS instruments continues to come from higher education and healthcare sectors, with notable procurement activities from institutions like Zhengzhou University and Guangzhou University of Chinese Medicine [10] - The East China region remains the largest market, accounting for 27.72% of total procurement, although procurement volume has decreased by 11.28% [12] Technology Trends - Triple quadrupole mass spectrometers dominate the market, accounting for 61.5% of all procurements, particularly in healthcare and regulatory applications [19] - Imported brands maintain a strong presence, with SCIEX, Thermo Fisher, and Waters leading the market shares at 28.9%, 21.9%, and 18.4% respectively [19][22] Future Outlook - The 2025 market may not represent a contraction but rather the beginning of a new phase of industrial restructuring, with potential for a multi-polar competitive landscape as domestic technology advances and user trust builds [25][26]