As filed with the Securities and Exchange Commission on October 14, 2025 Registration No. 333-289285 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 2 to Form F-3 on Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Psyence Biomedical Ltd. (Exact Name of Registrant as Specified in Its Charter) (State or Other Jurisdiction of Incorporation or Organization) Ontario, Canada 2834 Not Applicable (Primary Standard Industrial Classification Code Number) (I.R.S. ...

As filed with the Securities and Exchange Commission on October 6, 2025 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 to Form F-3 on Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Psyence Biomedical Ltd. (Exact Name of Registrant as Specified in Its Charter) (State or Other Jurisdiction of Incorporation or Organization) Ontario, Canada 2834 Not Applicable (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identification Numbe ...

Table of Contents As filed with the Securities and Exchange Commission on May 9, 2024 Registration No. 333-276973 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 3 to Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 (Primary Standard Industrial Classification Code Number) 121 Richmond Street West Penthouse Suite 1300 (I.R.S. Employer Identification Number) Toronto, Ontario MK5 2K1 Telephone: + 1 (416) 346-7764 (Address, including zip code, and telephone ...

Table of Contents As filed with the Securities and Exchange Commission on May 6, 2024 Registration No. 333-276973 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 2 to Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Psyence Biomedical Ltd. (Exact Name of Registrant as Specified in Its Charter) Ontario, Canada 2834 Not Applicable (State or Other Jurisdiction of Incorporation or Organization) (Primary Standard Industrial Classification Code Number) 121 Ric ...

Table of Contents As filed with the Securities and Exchange Commission on April 17, 2024 Registration No. 333-276973 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Amendment No. 1 to Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Psyence Biomedical Ltd. (Exact Name of Registrant as Specified in Its Charter) Ontario, Canada 2834 Not Applicable (State or Other Jurisdiction of Incorporation or Organization) (Primary Standard Industrial Classification Code Number) 121 ...

Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Psyence Biomedical Ltd. (Exact Name of Registrant as Specified in Its Charter) As filed with the Securities and Exchange Commission on February 9, 2024 Registration No. 333- (State or Other Jurisdiction of Incorporation or Organization) UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identification Number) 21 Richmond Street West Penthouse Suite 1 ...