Core Viewpoint - The recent study published by Jonas Frisen's team provides compelling evidence that neurogenesis continues in the adult human hippocampus, addressing a long-standing debate in neuroscience regarding the adaptability of the human brain [2][9]. Group 1: Research Findings - The study identifies proliferating neural progenitors in the adult human hippocampus, confirming that new neurons are generated even in late adulthood [2][6]. - The research utilized advanced techniques such as RNAscope and Xenium to locate these cells, confirming their presence in the dentate gyrus, a region critical for memory formation and cognitive flexibility [7][10]. - The findings indicate that human adult neural progenitor cells share similarities with those in mice, pigs, and monkeys, although there are differences in gene activity among individuals [8]. Group 2: Methodology - The research analyzed brain samples from individuals aged 0 to 78 years, revealing all stages of neural progenitor cells in early childhood and identifying proliferating progenitor cells in adults using the Ki67 antibody and machine learning algorithms [10]. - The study's methodology highlights the importance of single-cell transcriptomics in understanding the neurogenic environment in the adult human brain [11].