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TROP2癌症疫苗
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长江生命科技(00775)主席李泽钜:生物科技高回报高风险 纯收息买基建或收租股较适合
智通财经网· 2025-05-22 06:46
Core Viewpoint - The biotechnology sector is characterized by high returns and high risks, with successful products potentially surpassing the value of many listed infrastructure and real estate companies [1] Group 1: Company Strategy and Research - The company is currently engaged in multiple cancer vaccine research projects, including the TROP2 cancer vaccine, which has shown significant tumor growth inhibition in preclinical studies [1] - The TROP2 protein is overexpressed in various cancers, including triple-negative breast cancer, lung cancer, and colorectal cancer, with the company's vaccine demonstrating 100% tumor growth inhibition in mouse models [1] - The company estimates that it will take approximately 24-30 months to initiate Phase I/II clinical trials for the TROP2 vaccine [1] Group 2: Asset Management and Financial Strategy - The company considers its health products and agriculture-related businesses as important, generating stable cash flow to support research and development [1] - The company will continue to evaluate strategic options to enhance shareholder value and optimize its business structure, with any significant developments to be disclosed to the market [1] - There are currently no announcements regarding the potential spin-off of the biopharmaceutical division for a Hong Kong listing, and the company is assessing strategic opportunities to improve shareholder value [2] - The company has not announced any plans for fundraising through share placements or convertible bonds to support research and development [2]
长江生命科技(00775):针对 TROP2(滋养层细胞表面抗原 2)的新型癌症疫苗取得良好的早期成果 4月11日复牌
智通财经网· 2025-04-11 00:16
Group 1 - The company, Changjiang Life Science Technology, has announced promising early results from preclinical laboratory tests of a novel cancer vaccine targeting TROP2, a cell surface glycoprotein overexpressed in various cancers such as breast, lung, pancreatic, and colorectal cancers [1] - TROP2 plays a critical role in cell proliferation, metastasis, and invasion, making it a potential therapeutic target in oncology due to its high expression in cancer cells and minimal presence in normal tissues [1] - The TROP2 cancer vaccine candidate utilizes innovative circular RNA (circRNA) and fusion protein constructs, demonstrating significant tumor growth inhibition in preclinical studies involving over 170 mice, with complete tumor growth suppression observed in all breast cancer studies [1] Group 2 - The incidence of breast cancer, particularly triple-negative breast cancer (TNBC), is rising sharply in Asia, affecting many young women, with higher rates and severity compared to Western countries [2] - The company believes that the TROP2 cancer vaccine shows unprecedented anti-cancer efficacy based on mouse studies and aims to advance it to clinical research stages to provide new treatment options for patients [2] - The company has filed patent applications for the circRNA and fusion protein TROP2 cancer vaccine with the Hong Kong Intellectual Property Department and a provisional patent application with the U.S. Patent and Trademark Office [2] Group 3 - The company has applied to the Stock Exchange for the resumption of trading of its shares starting from 9:00 AM on April 11, 2025 [3]